Pseudorabies virus DNA polymerase processivity factor pUL42 inhibits type I IFN production by negatively regulating cGAS-STING signaling pathway. [PDF]
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Commentary: Development and immunogenicity evaluation of a quadruple-gene-deleted pseudorabies virus strain. [PDF]
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Isolation and molecular characteristics of a novel recombinant pseudorabies virus strain in Hunan province, China. [PDF]
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PRV gD-Based DNA Vaccine Candidates Adjuvanted with cGAS, UniSTING, or IFN-α Enhance Protective Immunity. [PDF]
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Epigenetic control of PRV-1 expression on neutrophils
Experimental Hematology, 2007Polycythemia rubra vera-1 (PRV-1) is a GPI-linked protein that is expressed on a subgroup of neutrophils. The number of PRV-1-expressing neutrophils increases in pregnancy and sepsis, or after administration of granulocyte colony-stimulating factor. Expression of the PRV-1 gene is also increased in patients with polycythemia vera (PV) and essential ...
Jaroslav, Jelinek +5 more
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PRV-1 mRNA expression discriminates two types of essential thrombocythemia
Annals of Hematology, 2004Essential thrombocythemia (ET) is a heterogeneous disorder. For example, the growth of erythropoietin-independent erythroid colonies, termed "endogenous erythroid colonies (EECs)", has previously been observed in only 50% of ET patients. We have recently described the overexpression of a hematopoietic receptor, PRV-1 (polycythemia rubra vera-1), in ...
Grießhammer, Martin +6 more
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The PRV-1 gene expression in essential thrombocythemia
Blood, 2004Recently, Temerinac and colleagues[1][1] found that the polycythemia rubra vera receptor-1 (PRV-1) m-RNA is increased in granulocytes of patients with polycythemia vera (PV) and in some cases of essential thrombocythemia (ET).
Teofili, Luciana +5 more
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Quantification of PRV-1 mRNA distinguishes polycythemia vera from secondary erythrocytosis
Blood, 2003To date, the diagnosis of polycythemia vera (PV) relies on clinical criteria. We have recently described the overexpression of a hematopoietic receptor, polycythemia rubra vera-1 (PRV-1), in patients with PV. Here, we report a quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) assay for the measurement of PRV-1 mRNA levels.
Steffen, Klippel +10 more
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Neutrophil and Eosinophil PRV-1 Expression in Atypical Myeloproliferative Disorders.
Blood, 2004Abstract Background : Neutrophil PRV-1 over-expression has been strongly associated with polycythemia vera (PV) and its quantitative measurement might complement the diagnostic distinction between PV and secondary polycythemia (Klippel et al. Blood2003;102:3569).
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