Results 51 to 60 of about 9,785 (151)

Suppression of ZBP1-mediated NLRP3 inflammasome by the tegument protein VP22 facilitates pseudorabies virus infection

mBio
The interaction between Z-DNA binding protein 1 (ZBP1) and the NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been uncovered in several viral infections.
Zicheng Ma, Depeng Liu, Wandi Cao, Lei Guo, Kesen Liu, Juan Bai, Xingyi Li, Ping Jiang, Xing Liu   +8 more
doaj   +1 more source

Evolution of the Piscine orthoreovirus Genome Linked to Emergence of Heart and Skeletal Muscle Inflammation in Farmed Atlantic Salmon (Salmo salar)

Viruses, 2019
Heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar) was first diagnosed in Norway in 1999. The disease is caused by Piscine orthoreovirus-1 (PRV-1).
Kannimuthu Dhamotharan, Torstein Tengs, Øystein Wessel, Stine Braaen, Ingvild B. Nyman, Elisabeth F. Hansen, Debes H. Christiansen, Maria K. Dahle, Espen Rimstad, Turhan Markussen   +9 more
doaj   +1 more source

PRV-1 Infected Macrophages in Melanized Focal Changes in White Muscle of Atlantic Salmon (Salmo salar) Correlates With a Pro-Inflammatory Environment. [PDF]

Front Immunol, 2021
Malik MS, Bjørgen H, Nyman IB, Wessel Ø, Koppang EO, Dahle MK, Rimstad E.   +6 more
europepmc   +1 more source

Pseudorabies virus induces ferroptosis by disrupting iron homeostasis through activation of TfR1 and ferritinophagy

Journal of Virology
Programmed cell death (PCD) refers to a regulated cellular process involving a cascade of biochemical reactions and molecular mechanisms, commonly including apoptosis, necroptosis, and pyroptosis.
Zicheng Ma, Lei Guo, Ran Ji, Zhe Sun, Jingyi Wang, Yang Yan, Kesen Liu, Hanhua Zhang, Xingya Wang, Chengyue Wu, Lin Lian, Wandi Cao, Juan Bai, Ping Jiang, Xing Liu   +14 more
doaj   +1 more source

Transcriptomics of early responses to purified Piscine orthoreovirus-1 in Atlantic salmon (Salmo salar L.) red blood cells compared to non-susceptible cell lines

Frontiers in Immunology
Piscine red blood cells (RBC) are nucleated and have been characterized as mediators of immune responses in addition to their role in gas exchange. Salmonid RBC are major target cells of Piscine orthoreovirus-1 (PRV-1), the etiological agent of heart and
Thomais Tsoulia, Thomais Tsoulia, Arvind Y. M. Sundaram, Arvind Y. M. Sundaram, Stine Braaen, Jorunn B. Jørgensen, Espen Rimstad, Øystein Wessel, Maria K. Dahle, Maria K. Dahle   +9 more
doaj   +1 more source

Persistent infection of Piscine orthoreovirus-1 (PRV-1) in Atlantic salmon (Salmo salar)

, 2021
This thesis focuses on infection kinetics, infected cell types, viral shedding, and specific immune responses in persistently Piscine orthoreovirus-1 (PRV-1) infected Atlantic salmon. The aim is to enhance the understanding of viral pathogenesis. PRV-1 is ubiquitous in Norwegian Atlantic salmon (Salmo salar) aquaculture. PRV-1 causes an acute infection
openaire   +1 more source

Consequences of Piscine orthoreovirus genotype 1 (PRV-1) infections in Chinook salmon (Oncorhynchus tshawytscha), coho salmon (O. kisutch) and rainbow trout (O. mykiss). [PDF]

J Fish Dis, 2020
Purcell MK, Powers RL, Taksdal T, McKenney D, Conway CM, Elliott DG, Polinski M, Garver K, Winton J.   +8 more
europepmc   +1 more source

Recombinant pseudorabies virus expressing the consensus VP2 protein of porcine parvovirus 1 (PPV1) protects pigs against pseudorabies virus and PPV1

Veterinary Research
Pseudorabies virus (PRV) and porcine parvovirus type 1 (PPV1) are major pathogens that cause reproductive disorders in sows, and mixed infections are frequently detected on pig farms.
Xiaoxiao Tian, Haojie Wang, Hao Song, Ziyi Wei, Xulong Zhu, Guoqing Liu, Mingxia Sun, Xinyi Huang, Meng Chen, Yandong Tang, Haiwei Wang, Yongbo Yang, Tongqing An   +12 more
doaj   +1 more source

Curcumin prevents dexamethasone-induced activation of the pseudorabies virus in rat pheochromocytoma cells through the miR-155-5p-Aak1-Numb/Notch2 signalling axis

Veterinary Research
Pseudorabies virus (PRV) causes neurological disorders and organ damage in diseased animals. After initial infection, PRV activity is gradually inhibited; however, stress stimulation increases the host’s glucocorticoid levels, which overcomes the ...
Naixiu Wang, Fan Yang, Zhiyun Qiu, Lin Zhang, Dingqiu Zou, Yanru Tang, Ruihan Zhang, Chenlu Sun, Pei Liu, Kexin Qi, Jingyi Wang, Hua He, Ling Gan   +12 more
doaj   +1 more source

Pulse Rate Variability Is Not the Same as Heart Rate Variability: Implications for Sports Performance and Injury Prevention. [PDF]

Sports Med Open
Ben-David K, Kantrowitz AB, Morris M, Renaghan EJ, Feigenbaum LA, Bellamy K, Girardi J, Wittels HL, Wishon MJ, McDonald SM, Wittels SH.   +10 more
europepmc   +1 more source