Results 41 to 50 of about 9,785 (151)

Pseudorabies virus gM and its homologous proteins in herpesviruses induce mitochondria-related apoptosis involved in viral pathogenicity.

PLoS Pathogens
Apoptosis is a critical host antiviral defense mechanism. But many viruses have evolved multiple strategies to manipulate apoptosis and escape host antiviral immune responses.
Qiongqiong Zhou, Deshi Shi, Yan-Dong Tang, Longfeng Zhang, Boli Hu, Chunfu Zheng, Li Huang, Changjiang Weng   +7 more
doaj   +1 more source

Mitofusin-Mediated Mitochondrial Fusion Inhibits Pseudorabies Virus Infection in Porcine Cells

Veterinary Sciences
Background: Mitochondria are highly dynamic organelles that undergo fusion/fission dynamics, and emerging evidence has established that mitochondrial dynamics plays a crucial regulatory role in the process of viral infection.
Xiuhan Xu, Yuan Zhao, Zhenbang Zhu, Wei Wen, Xiangdong Li   +4 more
doaj   +1 more source

Guanylate-binding protein 1 inhibits nuclear delivery of pseudorabies virus by disrupting structure of actin filaments

Veterinary Research, 2023
The alphaherpesvirus pseudorabies virus (PRV) is the causative agent of pseudorabies, responsible for severe economic losses to the swine industry worldwide.
Xiaohua Zhang, Qian Du, Guiyuan Chen, Yiyuan Jiang, Kai Huang, Linghao Li, Dewen Tong, Yong Huang   +7 more
doaj   +1 more source

Antiviral Activity of Diltiazem HCl Against Pseudorabies Virus Infection In Vitro

Veterinary Sciences
Pseudorabies virus (PRV) is a highly pathogenic agent that adversely impacts swine populations, leading to considerable economic losses within the Chinese pig industry.
Mengting Zuo, Decai Xiang, Zhen-Xing Zhang, Xi Yang, Yuqing Duan, Juan Li, Bangquan Zeng, Lu Dong, Guoquan Wu, Yi Zhou, Lei Tan, Bofang Duan   +11 more
doaj   +1 more source

Distinct effects of glucocorticoid on pseudorabies virus infection in neuron-like and epithelial cells

Journal of Virology
Pseudorabies virus (PRV) is a porcine neurotropic alphaherpesvirus that infects peripheral tissues of its host, spreads into the nervous system, and establishes a life-long latency in neuronal cells.
Zhengmin Lian, Yuan Zhao, Wei Wen, Zhenbang Zhu, Wenqiang Wang, Zhendong Zhang, Panrao Liu, Herman W. Favoreel, Xiangdong Li   +8 more
doaj   +1 more source

A wide extent of inter-strain diversity in virulent and vaccine strains of alphaherpesviruses.

PLoS Pathogens, 2011
Alphaherpesviruses are widespread in the human population, and include herpes simplex virus 1 (HSV-1) and 2, and varicella zoster virus (VZV). These viral pathogens cause epithelial lesions, and then infect the nervous system to cause lifelong latency ...
Moriah L Szpara, Yolanda R Tafuri, Lance Parsons, S Rafi Shamim, Kevin J Verstrepen, Matthieu Legendre, L W Enquist   +6 more
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The effects of hydroxyurea on PRV-1 expression in patients with essential thrombocythemia and polycythemia vera.

Haematologica, 2006
The study was designed to investigate the influence of hydroxyurea (HU) treatment on PRV-1 expression. Eighteen newly diagnosed patients with essential thrombocythemia (ET) or polycythemia vera (PV) were included. HU significantly increased PRV-1 gene expression in the early stage of treatment.
Peter, Johansson, Anne, Ricksten, Carina, Wasslavik, Berit, Johansson, Björn, Andréasson   +4 more
openaire   +1 more source

The host cells suppress the proliferation of pseudorabies virus by regulating the PI3K/Akt/mTOR pathway

Microbiology Spectrum
Pseudorabies virus (PRV), a member of the alpha-herpesviruses, can infect both the nervous and reproductive systems of pigs, causing neonatal mortality and reproductive failure in sows, which incurs substantial economic losses.
Lei Xu, Qian Tao, Yang Zhang, Feng-qin Lee, Tong Xu, Li-shuang Deng, Zhi-jie Jian, Jun Zhao, Si-yuan Lai, Yuan-cheng Zhou, Ling Zhu, Zhi-wen Xu   +11 more
doaj   +1 more source

Piscine orthoreovirus subtype 3 (PRV-3) causes heart inflammation in rainbow trout (Oncorhynchus mykiss)

Veterinary Research, 2019
Piscine orthoreovirus (PRV) mediated diseases have emerged throughout salmonid aquaculture. Three PRV subtypes are currently reported as causative agents of or in association with diseases in different salmonid species.
Niccoló Vendramin, Dhamotharan Kannimuthu, Anne Berit Olsen, Argelia Cuenca, Lena Hammerlund Teige, Øystein Wessel, Tine Moesgaard Iburg, Maria Krudtaa Dahle, Espen Rimstad, Niels Jørgen Olesen   +9 more
doaj   +1 more source

Regulatory effect of FEA on histone acetylation modification in immune cells induced by PRV infection in vivo and in vitro

Siliao yanjiu
The study aimed to observe the regulatory effect of the ethyl acetate fraction of Fagopyrum flavonoids (FEA) on histone acetylation modification in mice and cells infected with pseudorabies virus (PRV).
YU Xiaoli, YUAN Haifeng, HUANG Changqiao, JIANG Liqun, LI Yanhua, HU Xiaodong, REN Chunzhi, HU Tingjun   +7 more
doaj