ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
CRP at diagnosis in psoriatic arthritis: what it means and associations with long-term outcomes. [PDF]
Dimopoulou AE +36 more
europepmc +1 more source
Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley +1 more source
Stratified Analysis of Patients Within the PSA Gray Zone (4-10 ng/mL) and Its Clinical Application Value: Development of a Predictive Model for Clinically Significant Prostate Cancer Using Quantitative Indicators of PSA, ADC, and Relative T2 Value. [PDF]
Hao P, Zhu T, Xin R, Lv X.
europepmc +1 more source
Abstract Background Unilateral magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy reduces tremor in essential tremor, yet disability often persists on the untreated side. The added benefit and safety of a staged contralateral lesion remain uncertain.
Nima Norbu Sherpa +7 more
wiley +1 more source
Combination Treatment of IL-17 Inhibitor and JAK Inhibitor in Psoriatic Arthritis: A Case Report and Scoping Review. [PDF]
Pang M, Li L, Zhang Q, Zhao M.
europepmc +1 more source
Clinical Trial Protocol for LPS-Boost: Intensified [<sup>177</sup>Lu]Lu-PSMA-617 Treatment for Patients with Metastatic Castration-Resistant Prostate Cancer with Low PSMA-Expressing Disease. [PDF]
Iravani A +27 more
europepmc +1 more source
Delphi consensus of specialist radiologists on imaging criteria for gadolinium contrast use and whole-body MRI in prostate cancer. [PDF]
Onwuharine EN +3 more
europepmc +1 more source
Retrospective analysis of micronutrient status and prostate health: linking serum zinc, selenium, and vitamin D levels to prostate-specific antigen and urinary tract function. [PDF]
Feng C, Liu X, Nijiati S, Ma X, Yang H.
europepmc +1 more source
How low do you need to go? Association between various prostate-specific antigen response measures and clinical outcomes in metastatic castration-sensitive prostate cancer in the Veterans Health Administration data. [PDF]
Freedland SJ +7 more
europepmc +1 more source

