Results 171 to 180 of about 108,556 (242)

Bridging the gap in nutrition assessment: Barriers and knowledge impact of an educational session on body composition and energy metabolism

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Body composition and energy metabolism assessments are central to nutrition care but remain underused. This study evaluated dietitians’ access, use, education, and beliefs toward these assessments, and the impact of an educational session.
Camila E. Orsso   +17 more
wiley   +1 more source

Exploring the disease burden and quality of life in patients with short bowel syndrome with intestinal failure: Insights from exit interviews in the glepaglutide EASE SBS‐1 phase 3 trial

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background A randomized, double‐blind, placebo‐controlled trial was conducted to evaluate efficacy and safety of glepaglutide in patients who have short bowel syndrome with intestinal failure (SBS‐IF). At the end of the trial, exit interviews were conducted to explore participants' experiences and to assess the impact of the disease and ...
David F. Mercer   +5 more
wiley   +1 more source

A DUF3455 domain‐containing protein promotes Ustilaginoidea virens infection and functions as a plant immune elicitor

open access: yesNew Plant Protection, EarlyView.
The fungal effector UvDUF1 from Ustilaginoidea virens not only promotes infection but also acts as a plant immunity elicitor, inducing broad‐spectrum disease resistance in rice and Nicotiana benthamiana. These results reveal its potential as a novel target for sustainable crop protection strategies.
Shuchen Wang   +13 more
wiley   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

open access: yesChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel   +5 more
wiley   +1 more source

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