Results 71 to 80 of about 2,565,077 (232)

PSA DENSITY - A MARKER FOR POORLY-DIFFERENTIATED PROSTATE CANCER [PDF]

open access: yesJournal of IMAB
Purpose: The present study examines the relationship between Prostate-Specific Antigen Density (PSAD) and the degree of differentiation of prostate cancer, as determined by the Gleason score. Material/Methods: A single-center study was conducted.
Tosho Ganev
doaj   +1 more source

Platelet-to-lymphocyte ratio and systemic immune-inflammation index versus circulating prostate cells to predict significant prostate cancer at first biopsy

open access: yesUrology Research and Practice, 2020
Objective: It has been reported that the systemic immune-inflammation index (SII) and platelet-to-lymphocyte ratio (PLR) are higher in men with prostate cancer. We compare their use with the percentage of free prostate-specific antigen (PSA), PSA density,
Nigel P. Murray   +3 more
doaj   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

Kamus Istilah

open access: yes, 2012
Hal ...
PSA LAPAN
core  

TiO6 as a Compensatory Structural Unit in Co‐Free, High‐Ni Layered Oxide for Durable Lithium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
Ti substitution stabilizes Co‐free high‐Ni layered oxides through both structural and electronic effects. TiO6 octahedra act as compensatory structural units that help interrupt cooperative Jahn–Teller distortion and suppress detrimental phase transitions, while the electron‐withdrawing inductive effect of Ti stabilizes the oxygen lattice. As a result,
Bixian Ying   +19 more
wiley   +1 more source

Prostate-specific Antigen Density and Clinically Significant Prostate Cancer: Impact of Prostatic Volume in PI-RADS 3 Lesions; High Volume Single-center Analysis

open access: yesBulletin of Urooncology
Objective: Prostate-specific antigen density (PSAd) has gained traction as a superior diagnostic marker, compared with PSA alone, for predicting clinically significant prostate cancer (csPCa).
Çağrı Akpınar   +11 more
doaj   +1 more source

Predictive values for extracapsular extension in prostate cancer patients with PSA values below 10 ng/mL

open access: yesUrology Research and Practice, 2019
Objective: We aimed to determine predictive values of extracapsular extension (ECE) in patients who had undergone radical retropubic prostatectomy (RRP) with PSA values below 10 ng/mL.
Zülfü Sertkaya   +4 more
doaj   +1 more source

Sensitivity, Specificity, Positive predictive value (PPV), Negative predictive value (NPV) between MRI-PSA density and each US PSA density for the decision to biopsy at PSA threshold >0.12 ng/mL2.

open access: yes, 2022
Sensitivity, Specificity, Positive predictive value (PPV), Negative predictive value (NPV) between MRI-PSA density and each US PSA density for the decision to biopsy at PSA threshold >0.12 ng/mL2.
Vincent J. Gnanapragasam (8724540)   +5 more
core   +1 more source

Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation

open access: yesAdvanced Science, EarlyView.
Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Kongjun Liu   +8 more
wiley   +1 more source

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