Results 71 to 80 of about 81,829 (309)

Acute inactivation of PSD-95 destabilizes AMPA receptors at hippocampal synapses. [PDF]

PLoS ONE, 2013
Postsynatptic density protein (PSD-95) is a 95 kDa scaffolding protein that assembles signaling complexes at synapses. Over-expression of PSD-95 in primary hippocampal neurons selectively increases synaptic localization of AMPA receptors; however, mice ...
Guillermo A Yudowski, Olav Olsen, Hillel Adesnik, Kurt W Marek, David S Bredt   +4 more
doaj   +1 more source

Frequency-dependent and time-variant alterations of neural activity in post-stroke depression: A resting-state fMRI study

NeuroImage: Clinical, 2023
Background: Post-stroke depression (PSD) is one of the most frequent psychiatric disorders after stroke. However, the underlying brain mechanism of PSD remains unclarified.
Xiumei Wu, Luoyu Wang, Haibo Jiang, Yanhui Fu, Tiantian Wang, Zhenqiang Ma, Xiaoyan Wu, Yiying Wang, Fengmei Fan, Yulin Song, Yating Lv   +10 more
doaj   +1 more source

PSD performance and charge reconstruction with DAMPE [PDF]

Proceedings of 35th International Cosmic Ray Conference — PoS(ICRC2017), 2017
The DArk Matter Particle Explorer (DAMPE) is a satellite-borne device for detecting high energy electrons, gamma-rays, protons and heavy-ions in space. The Plastic Scintillator Detector (PSD) is the top-most of the four sub-detectors of DAMPE, which was designed to measure the charge of incident high-energy particles.
Y. Zhang, Y. Zhang, T. Dong, P. Ma, Y. Yu, P. Bernardini   +5 more
openaire   +2 more sources

Pyrolysis Induced Interphase and Structural Stabilization of Silicon‐Tin Disulfide/PAN Composite Electrode Materials for Li‐Ion Batteries

Advanced Materials Interfaces, EarlyView.
A Si and SnS2 based dual‐alloy anode material for metal‐ion battery applications with improved structural, interfacial and electrochemical properties is synthesized via a single‐step solid‐state pyrolysis process. During the pyrolysis step, SnS2 and Si are embedded in a porous, carbonized PAN‐based matrix, which is electronically and ionically ...
Akzhan Bekzhanov, Freddy Kleitz, Damian M. Cupid   +2 more
wiley   +1 more source

Flexible Implantable Silicon Carbide Multi‐Electrode Array (MEA) for Cell Multichannel Recording and Cell Ablation

Advanced Materials Technologies, EarlyView.
Flexible silicon carbide (SiC) microelectrode arrays enable high‐fidelity, multichannel cell extracellular recording and precise localized ablation. SiC has been extensively evaluated to persist long‐term in chronic physiological conditions while remaining robust, with excellent electrical and electrochemical stability.
Minh Anh Huynh, Matthew Barton, Sharda Yadav, Tuan‐Khoa Nguyen, Nam‐Trung Nguyen   +4 more
wiley   +1 more source

LIKELIHOOD FUNCTION BASED ON UNCENSORED/ CENSORED STATISTICAL DATA FOR MIN-PSD(MAX-PSD) AND MAX-PSD(MIN-PSD) AS LIFETIME DISTRIBUTIONS IN NETWORK RELIABILITY

JOURNAL OF ENGINEERING SCIENCE
In this paper general formulas for the likelihood function have been derived in the case when uncensored/censored statistical data refer to the lifetime of serial-parallel and parallel-serial type networks when the lifetimes of the system units are independent, identically distributed random variables, the number of subsystems and the number of units ...
Leahu, Alexei, Andrievschi-Bagrin, Veronica, Rotaru, Maria   +2 more
openaire   +2 more sources

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

Construction of a Risk Model Associated with Prognosis of Post-Stroke Depression Based on Magnetic Resonance Spectroscopy

Neuropsychiatric Disease and Treatment, 2020
Jialu Qiao,1 Rubo Sui,1 Lei Zhang,2 Jiannan Wang1 1Department of Neurology, First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, People’s Republic of China; 2School of Nursing, Jinzhou Medical University, Jinzhou, Liaoning ...
Qiao J, Sui R, Zhang L, Wang J
doaj  

PSD-95 and PSD-93 Play Critical But Distinct Roles in Synaptic Scaling Up and Down

, 2011
Synaptic scaling stabilizes neuronal firing through the homeostatic regulation of postsynaptic strength, but the mechanisms by which chronic changes in activity lead to bidirectional adjustments in synaptic AMPA receptor (AMPAR) abundance are ...
Qian Sun, Gina G. Turrigiano
core   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source