Results 81 to 90 of about 145,081 (341)

Rapid redistribution of synaptic PSD-95 in the neocortex in vivo. [PDF]

open access: yesPLoS Biology, 2006
Most excitatory synapses terminate on dendritic spines. Spines vary in size, and their volumes are proportional to the area of the postsynaptic density (PSD) and synaptic strength.
Noah W Gray   +3 more
doaj   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

open access: yesAdvanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis   +2 more
wiley   +1 more source

Disputas de poder político-partidário no Rio Grande do Sulpós-Estado Novo: o Diretório Leopoldense do PSD como estudo de caso (1945-1952)

open access: yesSemina
Este artigo tem por objetivo analisar, através da atuação do Diretório do Partido Social Democrático (PSD) de São Leopoldo, como ocorreram articulações e conflitos no processo de reestruturação partidária no Rio Grande do Sul na fase final do Estado Novo
Rodrigo Luis dos Santos
doaj   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

open access: yesAdvanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider   +14 more
wiley   +1 more source

Unificarea dreptei: testul parlamentarelor [PDF]

open access: yesPolis: Revista de Stiinte Politice, 2017
This is a incipient analysis which aim is to present some points of view that have coagulated in the short period since the general elections on December 11th, 2016.
Sabin DRĂGULIN, Silvia ROTARU
doaj  

Acute inactivation of PSD-95 destabilizes AMPA receptors at hippocampal synapses. [PDF]

open access: yesPLoS ONE, 2013
Postsynatptic density protein (PSD-95) is a 95 kDa scaffolding protein that assembles signaling complexes at synapses. Over-expression of PSD-95 in primary hippocampal neurons selectively increases synaptic localization of AMPA receptors; however, mice ...
Guillermo A Yudowski   +4 more
doaj   +1 more source

Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome

open access: yesJournal of Neuroscience, 2015
Fragile X syndrome (FXS) is caused by the loss of the fragile X mental retardation protein (FMRP), an RNA binding protein that regulates translation of numerous target mRNAs, some of which are dendritically localized.
Marius F Ifrim, K. Williams, G. Bassell
semanticscholar   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

The Relationship between PSD-95 Clustering and Spine Stability In Vivo

open access: yesJournal of Neuroscience, 2014
The appearance and disappearance of dendritic spines, accompanied by synapse formation and elimination may underlie the experience-dependent reorganization of cortical circuits.
Michele Cane   +3 more
semanticscholar   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo   +14 more
wiley   +1 more source

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