Results 91 to 100 of about 9,621 (218)

"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]

, 2007
Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core   +1 more source

Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells [PDF]

, 2017
Immunotoxins as antiviral therapeutics are largely unexplored but have promising prospective due to their high selectivity potential and their unparalleled efficiency.
Jeppesen, Mads G., Kledal, Thomas N., Krzywkowski, Karen, Malmgaard-Clausen, Mikkel, Rosenkilde, Mette M., Spiess, Katja   +5 more
core   +5 more sources

Pseudomonas aeruginosa exotoxin A and keratitis in mice.

Investigative ophthalmology & visual science, 2002
To determine the importance of Pseudomonas aeruginosa exotoxin A (ETA) as a virulence factor in corneal disease.Isogenic mutants deficient in ETA were constructed in P. aeruginosa strains PAO1 and ATCC 19660 by allelic exchange and then evaluated for virulence in a mouse model of bacterial keratitis.
Christopher M, Pillar, Jeffery A, Hobden
openaire   +1 more source

The Immunomodulatory Effect of Recombinant Exotoxin A of Pseudomonas Aeruginosa on Dendritic Cells Extracted from Mice Spleen

Journal of Fasa University of Medical Sciences, 2015
Background & Objective: Dendritic cell (DC) is as a key cell in activation of immune response against microbes and disease. Therefore, the effect of recombinant exotoxin A of Pseudomonas aeruginosa on the maturity and the activation of DCs was evaluated ...
Mohammad Hossein Karimi, Aziz Japoni, Manouchehr Rasouli, Salimeh Ebrahimnezhad   +3 more
doaj  

Effect of Mono and Di-rhamnolipids on Biofilms Pre-formed by Bacillus subtilis BBK006. [PDF]

, 2016
Different microbial inhibition strategies based on the planktonic bacterial physiology have been known to have limited efficacy on the growth of biofilms communities.
D Dubeau, DH Dusane, E Déziel, F Sepandj, F Villa, IM Banat, J Andrä, J Schindelin, JB Winterburn, LP Girard, M Benincasa, MA Díaz De Rienzo, MA Díaz De Rienzo, Mayri A. Díaz De Rienzo, ME Davey, ME Olson, P Setoodeh, Peter J. Martin, R Al-Tahhan, R Silva, SE Dowd, TJP Smyth, Y Yu, Y Zhang   +23 more
core   +2 more sources

Genes for carbon metabolism and the ToxA virulence factor in Pseudomonas aeruginosa are regulated through molecular interactions of PtxR and PtxS.

PLoS ONE, 2012
Homologs of the transcriptional regulator PtxS are omnipresent in Pseudomonas, whereas PtxR homologues are exclusively found in human pathogenic Pseudomonas species.
Abdelali Daddaoua, Sandy Fillet, Matilde Fernández, Zulema Udaondo, Tino Krell, Juan L Ramos   +5 more
doaj   +1 more source

Effect of Satureja khuzistanica essential oil (SKEO) extract on expression of lasA and lasB genes in Pseudomonas aeruginosa

Iranian Journal of Microbiology, 2019
Background and Objectives: Expressions of lasA and lasB genes of Pseudomonas aeruginosa are associated with bacterium pathogenicity. The present study was aimed to assess the effect of Satureja khuzistanica essential oil (SKEO) extract on expression of ...
Davoud Iman Islamieh, Davoud Afshar, Davoud Esmaeili   +2 more
doaj   +1 more source

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis [PDF]

, 2015
Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for pulmonary exacerbations,
Alan J. Knox, Alan R. Smyth, Andrew Clayton, Andrew W. Fogarty, David A. Barrett, David Honeybourne, Douglas L. Forrester, Edward F. Nash, Helen L. Barr, Jaffar-Bandjee, Jane Dewar, Joanna L. Whitehouse, Miguel Cámara, Nigel Halliday, Paul Williams, Rebecca Simms   +15 more
core   +2 more sources

Induction of murine cytolytic T lymphocytes by Pseudomonas aeruginosa exotoxin A [PDF]

Infection and Immunity, 1988
Pseudomonas aeruginosa exotoxin A (PA), a potent protein synthesis inhibitor, was found to be a weak T-cell mitogen for murine splenocytes. Maximal stimulation of [3H]thymidine incorporation was obtained with 10 to 100 ng of toxin per ml following a 4-day induction.
openaire   +2 more sources

Structural Insights into Pseudomonas aeruginosa Exotoxin A-Elongation Factor 2 Interactions: A Molecular Dynamics Study. [PDF]

J Chem Inf Model, 2023
Gholami A, Minai-Tehrani D, Mahdizadeh SJ, Saenz-Mendez P, Eriksson LA.   +4 more
europepmc   +1 more source