Results 31 to 40 of about 9,621 (218)

Contribution of the Twin Arginine Translocation system to the exoproteome of Pseudomonas aeruginosa [PDF]

, 2016
The opportunistic pathogen Pseudomonas aeruginosa uses secretion systems to deliver exoproteins into the environment. These exoproteins contribute to bacterial survival, adaptation, and virulence.
Antelmann, Haike, Ball, Genevieve, Gimenez, Maxime Remi, Imbert, Paul Roger Claude, Ize, Berengere, Voulhoux, Rome   +5 more
core   +3 more sources

Active immunization using exotoxin A confers protection against Pseudomonas aeruginosa infection in a mouse burn model

BMC Microbiology, 2009
Background Pseudomonas aeruginosa is an important cause of nosocomial infection and may lead to septicemia and death. We evaluated the immunogenicity of semi-purified exotoxin A from the bacterium in a mouse burn model.
Naghmachi Mohsen, Amini Masoud, Japoni Aziz, Mehrabani Davood, Kohanteb Jamshid, Manafi Ali, Zaghi Ahmad Hosseinzadeh, Khalili Nazanin   +7 more
doaj   +1 more source

Molecular identification of virulence genes of Pseudomonas aeruginosa isolated from fish (Cyprinus carpio) in Mosul city [PDF]

Iraqi Journal of Veterinary Sciences, 2022
Depending on the nature of the fish's environment, they are susceptible to many pathogens, including bacterial causes, so the goals of the current study are isolation and molecular identification of Pseudomonas aeruginosa with its prevalence rate and ...
Asmaa J. Altaee, Sumaya Y. Aldabbagh
doaj   +1 more source

Phase I clinical study of the recombinant antibody toxin scFv(FRP5)-ETA specific for the ErbB2/HER2 receptor in patients with advanced solid malignomas [PDF]

, 2005
Introduction: ScFv(FRP5)-ETA is a recombinant antibody toxin with binding specificity for ErbB2 (HER2). It consists of an N-terminal single-chain antibody fragment (scFv), genetically linked to truncated Pseudomonas exotoxin A (ETA).
Gunter von Minckwitz, Sebastian Harder, Sascha Hövelmann, Elke Jäger, Salah-Eddin Al-Batran, Sibylle Loibl, Akin Atmaca, Christian Cimpoiasu, Antje Neumann, Aklil Abera, Alexander Knuth, Manfred Kaufmann, Dirk Jäger, Alexander B Maurer, Winfried S Wels, MA Olayioye, Y Yarden, J Mendelsohn, DJ Slamon, CL Vogel, I Pastan, W Wels, RJ Kreitman, W Wels, W Wels, IM Harwerth, BH Iglewski, A Keppler-Hafkemeyer, M Schmidt, A Spyridonidis, M Azemar, L Wang, U Altenschmidt, M Maurer-Gebhard, JK Batra, Y Reiter, LH Pai-Scherf, M Azemar, WMA, M Maurer-Gebhard, FDA, J Schumann, M Onda, NJ Olsen, YL Yip, B Gerstmayer, DL Keefe, HS Cho, RJ Kreitman, RJ Kreitman   +49 more
core   +1 more source

Pseudomonas aeruginosa exotoxin A-induced hepatotoxicity in dynamics: an animal model in white mice [PDF]

Саратовский научно-медицинский журнал, 2015
Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of ...
Morrison A.V., Popovich V.I., Morrison V.V.   +2 more
doaj  

Prevalence of exoT Gene in Pseudomonas aeruginosa Isolated from Various Clinical Samples: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Pseudomonas aeruginosa (P. aeruginosa) is one of the most frequently co-infecting bacteria reported. Development of drug resistance, biofilm formation, cell associated factors make the P. aeruginosa more virulent.
Jagannath Dnyanoba Andhale, M Anjaneya Swamy, RN Misra   +2 more
doaj   +1 more source

Novel approaches to the treatment of Pseudomonas aeruginosa infections in cystic fibrosis [PDF]

, 2012
Pseudomonas aeruginosa chronically infects patients with cystic fibrosis and is associated with greater morbidity. There has been limited progress on the clinical development of new antibiotics with novel modes of action.
Cámara, Miguel, Hurley, M.N., Smyth, Alan R.   +2 more
core   +2 more sources

Ferric uptake regulator Fur is conditionally essential in Pseudomonas aeruginosa [PDF]

, 2017
In Pseudomonas aeruginosa, the ferric uptake regulator (Fur) protein controls both metabolism and virulence in response to iron availability. Differently from other bacteria, attempts to obtain fur deletion mutants of P. aeruginosa failed, leading to the
Banin, Ehud, Genah, Shirley, Imperi, Francesco, Lo Sciuto, Alessandra, Pasqua, Martina, Visaggio, Daniela, Visca, Paolo   +6 more
core   +1 more source

Role of Vfr in regulating exotoxin A production by Pseudomonas aeruginosa [PDF]

Microbiology, 2009
Pseudomonas aeruginosaexotoxin A (ETA) production depends on the virulence-factor regulator Vfr. Recent evidence indicates that theP. aeruginosairon-starvation sigma factor PvdS also enhances ETA production through the ETA-regulatory generegA. Mutants defective invfr,regAandpvdS, plasmids that overexpress these genes individually andlacZtranscriptional/
Marko, Davinic, Nancy L, Carty, Jane A, Colmer-Hamood, Michael, San Francisco, Abdul N, Hamood   +4 more
openaire   +2 more sources

Analysis of immunization with DNA encodingPseudomonas aeruginosaexotoxin A [PDF]

FEMS Immunology & Medical Microbiology, 2000
The promising arena of DNA-based vaccines has led us to investigate possible candidates for immunization against bacterial pathogens. One such target is the opportunistic pathogen Pseudomonas aeruginosa which produces exotoxin A (PE), a well-characterized virulence factor encoded by the toxA gene.
K S, Denis-Mize, B M, Price, N R, Baker, D R, Galloway   +3 more
openaire   +2 more sources