Results 131 to 140 of about 192,572 (266)

Broad‐Spectrum Antimicrobial and Biofilm‐Disrupting Activity of D7: A Novel Disinfectant Effective Against Pseudomonas aeruginosa and Other Clinically Relevant Pathogens

iNew Medicine, EarlyView.
ABSTRACT Biofilm‐associated contamination and the presence of multiple pathogenic species on environmental and medical surfaces pose a major challenge in healthcare and hygiene management, contributing significantly to hospital‐acquired infections (HAIs).
Shanghui Gao, Kai Yang, Kunlong Zhang, Yunhao Wu, Jianrong Zhou, Kazumi Yokomizo, Jun Fang   +6 more
wiley   +1 more source

Expression of Interleukin-6 in the Cornea in Response to Infection with Different Strains ofPseudomonas aeruginosa [PDF]

, 1999
Nerida Cole, Shisan Bao, Mark Willcox, Alan J. Husband   +3 more
openalex   +1 more source

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

In vivo oral efficacy of levofloxacin for treatment of systemic Pseudomonas aeruginosa infections in a murine model of septicemia [PDF]

, 1996
Susan K. Yagel, John F. Barrett, Dhammika Amaratunga, Mary Beth Frosco   +3 more
openalex   +1 more source

Advances and challenges in point‐of‐care testing for pathogenic bacteria in battlefield injuries

Interdisciplinary Medicine, EarlyView.
This review explores trauma‐associated bacterial species, summarizes these biosensor advancements, addresses fabrication challenges, outlines future directions, and aims to guide POCT biosensor development for combat/trauma care bacterial detection.
Junjie Fan, Shuai Liu, Dan Luo, Hengjun Zhang, Xianling Dai, Hanqing Xu, Man Shen, Yingchun Huang, Yupeng Long, Ming Chen, Qiaofeng Li, Jing Bao   +11 more
wiley   +1 more source

New Pseudomonas infections drive Pf phage transmission in CF airways. [PDF]

JCI Insight
Pourtois JD, Haddock NL, Gupta A, Khosravi A, Martinez HA, Schmidt AK, Prakash PS, Jain R, Fleming P, Chang TH, Milla C, Secor PR, De Leo GA, Bollyky PL, Burgener EB.   +14 more
europepmc   +1 more source

Pseudomonas Aeruginosa in Oral Infections

, 1972
C. E. Nord, Lennart Sjöberg, Torkel Wadström   +2 more
openalex   +1 more source

Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Using Humanized Dosing Schemes [PDF]

, 2017
Rajbharan Yadav, Jürgen B. Bulitta, Jiping Wang, Roger L. Nation, Cornelia B. Landersdorfer   +4 more
openalex   +1 more source

LIN‐24 as a Molecular Switch: Dual Cytotoxic and Cytoprotective Roles of an Aerolysin‐Like Protein in C. elegans

Journal of Applied Toxicology, EarlyView.
ABSTRACT LIN‐24, an aerolysin‐like pore‐forming protein in Caenorhabditis elegans, exemplifies how ancient cytolytic mechanisms have evolved into regulated cellular processes. Initially identified for inducing nonapoptotic, engulfment‐dependent cell death in vulval precursor cells, LIN‐24 has emerged as a multifunctional regulator of metabolism, stress
Sharoen Yu Ming Lim
wiley   +1 more source

Strategies for the biocontrol Pseudomonas infections pre-fruit harvest. [PDF]

Microb Biotechnol
Warring SL, Sisson HM, Fineran PC, Rabiey M.   +3 more
europepmc   +1 more source