Results 141 to 150 of about 3,746,898 (399)

Trimetallic Nanozyme‐Embedded Smart Hydrogel Enables NIR‐Controlled Bacterial Killing and Oxidative Stress Alleviation

open access: yesAdvanced Science, EarlyView.
A microenvironment‐responsive hydrogel is developed incorporating polymyxin B‐modified AuMnCu nanozymes and dual drugs (tannic acid and tobramycin). At infection sites, it generates ROS, releases drugs responsively, and enhances mild photothermal action to disrupt bacterial redox balance.
Zehui Xiao   +5 more
wiley   +1 more source

Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts

open access: yesAdvanced Science, EarlyView.
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song   +7 more
wiley   +1 more source

INHALED COLISTIN USE IN A NEUTROPENIC PATIENT.

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Fifty nine years old man who was diagnosed as mantle cell lymphoma   relapsed after high dose chemotherapy with peripheral stem cell rescue. One course of R- Hyper CVAD regimen  followed by high dose metotreaxate and cytrabine regimen was applied.
Figen Atalay   +2 more
doaj  

The Determination of Metallo-Beta-Lactamase Enzymes Prevalence in Pseudomonas Aeruginosa using Etest and their Antibiogram Patterns in Kermanshah, Iran [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2015
Background & Aims: One of the main causes of nosocomial infection is pseudomonas aeruginosa and carbapenems is one of the most important classes of antibiotics used in the treatment of infections caused by this bacteria.
Hossein Fazeli   +2 more
doaj  

Preliminary Analysis of the Anti-biofilm Efficacy of Manuka Honey on Extended Spectrum Β-lactamase Producing Escherichia Coli Tem-3 and Klebsiella Pneumoniae Shv18, Associated with Urinary Tract Infections [PDF]

open access: yes, 2019
open access articleUrinary Tract Infections (UTIs) are one of the most common infections in the UK and many other parts of the world. The prevalence of the Extended Spectrum β-Lactamases (ESBLs) producing UTIs, combined with their ability to form a bio ...
Baho, S.   +2 more
core  

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

open access: yesAdvanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal   +3 more
wiley   +1 more source

Antimicrobial Resistance Profile of Pseudomonas Aeruginosa Strains

open access: yesMedical Laboratory Journal, 2015
Background and Objectives: Pseudomonas aeruginosa is the most common organism, which is separated from the burn infections.  Due to increased antibiotic resistance, there are many problems to deal with the infections caused by Pseudomonas aeruginosa ...
Shafiee, F   +4 more
doaj  

Noninvasive Combined Diagnosis and Monitoring of Aspergillus and Pseudomonas Infections: Proof of Concept. [PDF]

open access: yesJ Fungi (Basel), 2021
Dobiáš R   +13 more
europepmc   +1 more source

Collaborative Cross Mice Yield Genetic Modifiers for Pseudomonas aeruginosa Infection in Human Lung Disease

open access: gold, 2020
Nicola Ivan Lorè   +8 more
openalex   +1 more source

Synovial Fluid‐derived Micrococcus Luteus G18 Exacerbates Osteoarthritis Progression by Promoting Chondrocyte Degradation via TLR2/JNK/AP‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen   +6 more
wiley   +1 more source

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