Results 81 to 90 of about 2,121 (171)

Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5‐HT2A receptor

British Journal of Pharmacology, Volume 183, Issue 19, Page 5871-5894, October 2026.
A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga, Robert Kronstrand, Bianca Schranz, Nick van Zijl, Sebastian Karlman, Soma Aref, Tobias Rautio, Svante Vikingsson, Mattias Persson, Henrik Green   +9 more
wiley   +1 more source

Psilocybin Use in an Intercollegiate Athlete with Persisting Symptoms After Concussion: A Case Report

Psychoactives
Background: Persisting symptoms after concussion is a complex syndrome warranting exploration into further treatment options. Emerging research highlights the potential of classic psychedelics, such as psilocybin, in managing neuropsychiatric conditions ...
David W. Lawrence, Alex P. Di Battista, Michael G. Hutchison   +2 more
doaj   +1 more source

Binding Interactions of Psilocin and Serotonin in the 5-HT2A Receptor

, 2020
Psilocin is a molecule found in psilocybin mushrooms, which are typically consumed recreationally for their hallucinogenic effects. Recently, studies have shown that psilocin can have almost immediate antidepressant effects in patients who are treatment ...
Lewis, Stephanie N., Barnes, Katie
core  

Effects of hallucinogenic drugs on the human heart

Frontiers in Pharmacology
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain.
Joachim Neumann, Stefan Dhein, Uwe Kirchhefer, Britt Hofmann, Ulrich Gergs   +4 more
doaj   +1 more source

CeA Psilocin fiber photometry study: Data and custom code from experiments looking at changes in calcium dynamics in response to an air puff events

, 2022
Psilocybin, and its active metabolite psilocin, have been shown to elicit rapid and long-lasting symptom improvements in a variety of affective psychiatric illnesses.
Effinger, Devin
core   +1 more source

Sex-specific effects in affective behavior, alcohol drinking, amygdala activation and the impact of the psychedelic psilocin in mice [PDF]

Alcohol use disorder (AUD) is a multifaceted, chronic condition characterized by a compulsion to drink despite the emergence of social, medical, and psychological consequences.
Magee, Sarah
core   +1 more source

Determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2'-bypyridyl) ruthenium(II) chemiluminescence detection respectively

, 2005
Asimple, rapid and sensitive method for the determination of psilocin and psilocybin is described. This is the first report on the determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2 ...
Gathergood, N., Sims, D., Anastos, N., Scammells, P., Barnett, N., Lewis, Simon   +5 more
core   +2 more sources

Pholiotina cyanopus, a rare fungus producing psychoactive tryptamines

Open Life Sciences, 2014
Pholiotina cyanopus was collected from wood chips and other woody remnants of undetermined tree species. Its basidiomata were found in June within the area of closed sawmill in the central part of Żywiec city (SW Poland).
Halama Marek, Poliwoda Anna, Jasicka-Misiak Izabela, Wieczorek Piotr P., Rutkowski Ryszard   +4 more
doaj   +1 more source

Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives

Pharmaceuticals
The Psilocybe genus is known for producing tryptamine alkaloids, specifically the compounds psilocybin and psilocin, which have shown antidepressant and anxiolytic potential.
Mateus A. Luz, Hellen V. S. Guedes, Antônio B. M. Bisneto, Raquel A. de Jesus, Taynah P. Galdino, Lucas C. Oliveira, Victor Ignacio Afonso, Marcus Vinícius L. Fook, Antônio G. B. Lima, Suedina M. de L. Silva, Maria C. M. Torres   +10 more
doaj   +1 more source

A brief perturbation. A broad transcriptional signature: psilocin human-neuron transcriptomics

Christopher B. Germann
  +4 more sources