Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature [PDF]
Ecology and EvolutionResearch into psychedelic compounds is in resurgence because of the exciting potential for their use in the treatment of psychiatric and mental health disorders. Despite this revival, remarkably little is known about their evolution.
K. J. Matthews Nicholass +16 more
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Exploring Psilocybe spp. mycelium and fruiting body chemistry for potential therapeutic compounds [PDF]
Frontiers in Fungal Biology, 2023 Psilocybe mushrooms, otherwise known as “magic” mushrooms, owe their psychedelic effect to psilocin, a serotonin subtype 2A (5-HT2A) receptor agonist and metabolite of psilocybin, the primary indole alkaloid found in Psilocybe species. Metabolomics is an
Adam Waldbillig +4 more
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Three New Fungi from China: A Potentially Psychoactive Psilocybe and Two Deconica Species [PDF]
Journal of FungiThe saprotrophic genera Deconica and Psilocybe exhibit broad geographic distributions across temperate and subtropical biomes globally. Despite China’s rich fungal diversity, taxonomic studies of these genera remain limited, with few species previously ...
Hai-Ying Feng +4 more
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Frontiers in Forests and Global Change, 2022 Psilocybin and psilocin, two psychoactive components found in “magic mushrooms,” have therapeutic potential in a number of mental health disorders without the addictiveness and overdose risks found in other mind-altering drugs, such as cocaine ...
Soumya Ghosh +2 more
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Current use of holy mushrooms of the genus Psilocybe in a Zapotec community in Oaxaca, Mexico [PDF]
IMA FungusThe use of psychoactive Psilocybe mushrooms as entheogens by the Mazatecs of Oaxaca became known to the world in 1957. While the Mazatec Region has been the focus of research, historical records indicate that other indigenous groups in Mexico, including ...
Mara Ximena Haro-Luna +4 more
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Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives [PDF]
PharmaceuticalsThe Psilocybe genus is known for producing tryptamine alkaloids, specifically the compounds psilocybin and psilocin, which have shown antidepressant and anxiolytic potential.
Mateus A. Luz +10 more
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Extraction Yields of Psilocybin and Psilocin: A Short Review of Current Methods and Their Implications [PDF]
PharmaceuticalsThe growing body of evidence supporting the therapeutic efficacy of psychoactive substances, like psilocybin, has driven significant interest in recent decades due to their low toxicity and potential applications in treating various mental health ...
Taynah P. Galdino +11 more
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Mycelium Growth and Development of Psilocybe spp. Mother Cultures on Agar-Based Media [PDF]
Journal of FungiThe resurgence of interest in the therapeutic potential of psilocybin-producing mushrooms has recently led to numerous research and commercialization efforts.
Marco Pepe +4 more
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Cultivation, chemistry, and genome of <i>Psilocybe zapotecorum</i>. [PDF]
J Psychedelic Stud, 2023 AbstractPsilocybe zapotecorumis a strongly blue-bruising psilocybin mushroom used by indigenous groups in southeastern Mexico and beyond. While this species has a rich history of ceremonial use, research into its chemistry and genetics have been limited.
Miller DR +7 more
europepmc +3 more sources
A draft reference assembly of the Psilocybe cubensis genome [version 2; peer review: 2 approved] [PDF]
F1000Research, 2021 We describe the use of high-fidelity single molecule sequencing to assemble the genome of the psychoactive Psilocybe cubensis mushroom. The genome is 46.6Mb, 46% GC, and in 32 contigs with an N50 of 3.3Mb. The BUSCO completeness scores are 97.6% with 1.2%
Kevin McKernan +5 more
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