Results 11 to 20 of about 4,546 (198)

Psilocybe cubensis (Agaricales, Basidiomycota) en Ecuador

Lilloa, 2021
Psilocybe cubensis es una especie con propiedades alucinógenas utilizada tradicionalmente por diversas comunidades originarias, pero más recientemente, utilizada con fines recreativos, a pesar de su ilegalidad.
Giovanna Alban-J., Maria del Carmen Terán, María Robles-U., Francisco Quinde, Nicolás Niveiro   +4 more
doaj   +5 more sources

Exploring Psilocybe cubensis Strains: Cultivation Techniques, Psychoactive Compounds, Genetics and Research Gaps [PDF]

Journal of Fungi
Psilocybe cubensis, a widely recognized psychoactive mushroom species, has played a significant role in both historical and modern therapeutic practices.
Eyal Kurzbaum, Tomáš Páleníček, Amiel Shrchaton, Sara Azerrad, Yaron Dekel   +4 more
doaj   +2 more sources

Psilocybe cubensis y Panaeolus cyanescens (Basidiomycota, Agaricales), dos especies de hongos alucinógenos en el NE de Argentina

Boletín de la Sociedad Argentina de Botánica
Introducción y Objetivos: Algunas especies de hongos pueden inducir alucinaciones causadas por compuestos como la psilocibina, y numerosos estudios han examinado su potencial como tratamientos para diversas enfermedades. Este trabajo tiene como objetivo
Adriana Judit Batista, Hugo A. Almirón, Gisela Forlin, Natalia A. Ramírez, Orlando F. Popoff, Nicolás Niveiro   +5 more
doaj   +2 more sources

Genetic regulation of l-tryptophan metabolism in Psilocybe mexicana supports psilocybin biosynthesis [PDF]

Fungal Biology and Biotechnology
Background Although Basidiomycota produce pharmaceutically and ecologically relevant natural products, knowledge of how they coordinate their primary and secondary metabolism is virtually non-existent.
Paula Sophie Seibold, Sebastian Dörner, Janis Fricke, Tim Schäfer, Christine Beemelmanns, Dirk Hoffmeister   +5 more
doaj   +2 more sources

Development of a PBPK model of psilocybin/psilocin from Psilocybe cubensis (magic mushroom) in mice, rats, and humans [PDF]

Scientific Reports
Psilocybin is an active alkaloid found in magic mushrooms (Psilocybe cubensis). It is classified as a Class I Psychoactive Substance due to its psychoactive properties.
Nilubon Thaoboonruang, Ornrat Lohitnavy, Kimheang Ya, Manupat Lohitnavy   +3 more
doaj   +2 more sources

Specific and Multi-Product Clade I and Clade IV Sesquiterpene Synthases Contribute to the Psilocybe cubensis Volatilome. [PDF]

Chembiochem
Five sesquiterpene synthases of Psilocybe cubensis were investigated in vitro and in vivo. CubF is a clade I synthase producing α‐muurolol, whereas clade IV synthases CubG1 and CubG2 produce epi‐isozizaene and β‐duprezianene. Further clade IV synthases CubH and CubI primarily make dauca‐4(11),8‐diene and β‐barbatene, respectively.
Schober S, Dorfmann L, Walther K, Blei F, Chadeayne AR, Gressler M, Bartram S, O'Connor SE, Hoffmeister D.   +8 more
europepmc   +2 more sources

Current situation regarding psychedelics and magic mushroom in Korea [PDF]

European Psychiatry
Introduction Recently, the pros and cons have been debating in Korea even before the approval of use of medical marijuana with very strict limitations. And the next controversial topic is psychedelics.
J. S. Seo
doaj   +2 more sources

Dissimilar Reactions and Enzymes for Psilocybin Biosynthesis in Inocybe and Psilocybe Mushrooms. [PDF]

Angew Chem Int Ed Engl
Mushrooms have learned twice independently how to make the iconic magic mushroom natural product psilocybin. This article introduces the enzymes of the second pathway, found in a fiber cap mushroom. Curiously, the two pathways do not share any reaction, nor do the enzymes show a close relationship, but both pathways proceed via 4‐hydroxytryptamine as a
Schäfer T, Haun F, Rupp B, Hoffmeister D.   +3 more
europepmc   +2 more sources

Clade III Synthases Add Cyclic and Linear Terpenoids to the Psilocybe Metabolome. [PDF]

Chembiochem
The Psilocybe cubensis terpene synthases, CubB‐CubE, were investigated. Product formation assays identified CubB as a (3R,6E)‐(‐)‐nerolidol or linalool synthase, whereas CubC is a multiproduct synthase catalyzing the formation of β‐caryophyllene and other linear and cyclic sesquiterpenes/‐terpenoids.
Zschoche N, Schober S, Walther K, Chadeayne AR, Gressler M, Bartram S, O'Connor SE, Hoffmeister D.   +7 more
europepmc   +2 more sources

Genetic Survey of Psilocybe Natural Products

ChemBioChem, 2022
AbstractPsilocybe magic mushrooms are best known for their main natural product, psilocybin, and its dephosphorylated congener, the psychedelic metabolite psilocin. Beyond tryptamines, the secondary metabolome of these fungi is poorly understood. The genomes of five species (P. azurescens, P. cubensis, P. cyanescens, P. mexicana, and P.
Sebastian Dörner, Kai Rogge, Janis Fricke, Tim Schäfer, Jacob M. Wurlitzer, Markus Gressler, Duyen N. K. Pham, David R. Manke, Andrew R. Chadeayne, Dirk Hoffmeister   +9 more
openaire   +2 more sources