Results 31 to 40 of about 15,597 (227)
Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
core +1 more source
Reaction of N,N-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions. [PDF]
, 2018 A large number of clinically used drugs and experimental pharmaceuticals possess the N,N-dimethyltryptamine (DMT) structural core. Previous reports have described the reaction of this motif with dichloromethane (DCM), a common laboratory solvent used ...
Dunlap, Lee E, Olson, David E
core +3 more sources
Differential effects of MDMA and methylphenidate on social cognition [PDF]
, 2014 Social cognition is important in everyday-life social interactions. The social cognitive effects of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and methylphenidate (both used for neuroenhancement and as party drugs) are largely unknown.
Crockett, Molly J. +5 more
core +1 more source
Therapeutic use of psilocybin: Practical considerations for dosing and administration
Frontiers in Psychiatry, 2022 The interest in psilocybin as a therapeutic approach has grown exponentially in recent years. Despite increasing access, there remains a lack of practical guidance on the topic for health care professionals.
Caroline A. MacCallum +3 more
doaj +1 more source
Will psilocybin lose its magic in the clinical setting?
Therapeutic Advances in Psychopharmacology, 2022 Psilocybin as a novel treatment for depression is garnering a lot of attention from both the mainstream media and the academic community. Although phase 3 trials are only just beginning, we feel that it is important for clinicians to consider what ...
Caroline Hayes +2 more
doaj +1 more source
De Novo Biosynthesis of Antidepressant Psilocybin in Escherichia coli
Microbial BiotechnologyPsilocybin, a tryptamine‐derived alkaloid, has been granted Breakthrough Therapy designation by the U.S. FDA for treatment‐resistant depression, underscoring its clinical importance.
Zhangrao Huang +5 more
doaj +1 more source
A Revised Model for Muscarine Biosynthesis Involving Lysine Trimethylation
Angewandte Chemie International Edition, EarlyView.The fatal mushroom toxin l‐(+)‐muscarine is one of the most prominent natural products. We elucidated its biosynthetic origin in the sweating mushroom Collybia rivulosa based on incorporation of stable isotope‐labeled compounds and extensive mass spectrometric analyses.
Sebastian Dörner +4 more
wiley +1 more source
Advances in Sample Preparation, 2023 Vacuum-assisted headspace high capacity solid-phase microextraction (Vac-HS-HC-SPME) coupled with gas chromatography–mass spectrometry (GC–MS) was used to compare the volatile compounds that make up the volatile and semi-volatile components of five ...
Shannon L. Thomas +2 more
doaj +1 more source
Drug Testing and Analysis, EarlyView.Combined self‐report and hair analysis in festival attendees (n = 249) revealed substantial discrepancies in drug use reporting, particularly for stimulants and dissociatives. This integrated approach enhances detection of poly‐drug use and provides a more reliable basis for monitoring and harm‐reduction strategies.
A. Y. Simão +4 more
wiley +1 more source
Nature CommunicationsPsilocybin increases social connectedness and has strong clinical transdiagnostic efficacy for mental illness, making it a candidate treatment to reduce maternal disconnect, anxiety, and blunted affect seen in peripartum mood disorders.
Cassandra J. Hatzipantelis +15 more
doaj +1 more source