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The Therapeutic Potential of Psilocybin
Molecules, 2021 The psychedelic effects of some plants and fungi have been known and deliberately exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal source of naturally occurring psychedelics.
Henry Lowe +7 more
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Psilocybin sex-dependently reduces alcohol consumption in C57BL/6J mice
Frontiers in Pharmacology, 2023 The classical psychedelic psilocybin is of interest as a treatment for alcohol use disorder (AUD). This study investigated the effects of psilocybin on voluntary ethanol consumption in adult male and female C57BL/6J mice administered saline or psilocybin
Kenneth Alper +9 more
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Psilocybin-Assisted Compassion Focused Therapy for Depression
Frontiers in Psychology, 2022 Psilocybin-assisted psychotherapy, i.e., psilocybin treatment with psychological support, has demonstrated the efficacy of psilocybin to reduce depressive symptoms.
Wendy Pots, Farid Chakhssi
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A systematic review to assess the use of psilocybin in the treatment of headaches
European Psychiatry, 2023 Introduction Psilocybin is a naturally occurring psychedelic compound whose effects have been seen in studies for treatment of depression, anxiety and pain management.
S. Bhanot +4 more
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The Effects of Daytime Psilocybin Administration on Sleep: Implications for Antidepressant Action
Frontiers in Pharmacology, 2020 Serotonergic agonist psilocybin is a psychedelic with antidepressant potential. Sleep may interact with psilocybin’s antidepressant properties like other antidepressant drugs via induction of neuroplasticity. The main aim of the study was to evaluate the
Daniela Dudysová +28 more
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Effectiveness of Psilocybin on Depression: A Qualitative Study
, 2021 Introduction: Psilocybin mushroom use is well documented in spiritual and religious ceremonies globally. This drug is now the most popular in Europe and the USA.
Erlam, G, Alshaikhli, H, Al-Naggar, RA
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Psilocybin facilitates fear extinction in mice by promoting hippocampal neuroplasticity
Chinese Medical Journal, 2023 . Background:. Posttraumatic stress disorder (PTSD) and depression are highly comorbid. Psilocybin exerts substantial therapeutic effects on depression by promoting neuroplasticity.
Yingjie Du +7 more
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Knocking on the Doors of Perception: the role of psilocybin in substance use disorder treatment
European Psychiatry, 2023 Introduction Substance use disorders(SUDs) are a major health concern and current treatment interventions have proven only limited success. Despite increasing effectiveness, still about 50–60% relapse within 6–12 months after treatment [Cornelius et al.,
R. Sousa +9 more
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NeuroImage, 2021 Hallucinogenic agents have been proposed as potent antidepressants; this includes the serotonin (5-HT) receptor 2A agonist psilocybin. In human subjects, psilocybin alters functional connectivity (FC) within the default-mode network (DMN), a ...
Joanes Grandjean +7 more
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Scientific Reports, 2023 Psilocybin and lysergic acid diethylamide (LSD) experiences can range from very positive to highly challenging (e.g., fear, grief, and paranoia). These challenging experiences contribute to hesitancy toward psychedelic-assisted psychotherapy among health
Richard J. Zeifman +7 more
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