PHOTOCHEMISTRY AND PHOTOBIOLOGY OF PSORALENS [PDF]
Photochemistry and Photobiology, 1979 Abstract— The photochemistry and photobiology of psoralens have been rcvicwed on the basis of selected literature. In addition to the well establishcd photoaddition of psoralens to DNA. photoreac‐tions involving RNA. tRNA and proteins warrant further studies.
Kenneth J. Tapley, Pill-Soon Song
openaire +3 more sources
Incidence and Risk Factors Associated with a Second Squamous Cell Carcinoma or Basal Cell Carcinoma in Psoralen + Ultraviolet A Light-treated Psoriasis Patients [PDF]
, 2002 Psoralen + ultraviolet A-treated psoriasis patients are at increased risk for squamous cell carcinomas and basal cell carcinomas; however, the incidence and risk factors associated with second squamous cell carcinomas and basal cell carcinomas in this ...
Katz, Kenneth A. +2 more
core +1 more source
Psoralen induced cell cycle arrest by modulating Wnt/β-catenin pathway in breast cancer cells
Scientific Reports, 2018 Psoralen could inhibit the proliferation of human breast cancer cells, however, the molecular mechanism was unclear. We evaluated the anti-proliferative effects of psoralen by MTT, plate colony formation assay and cell cycle analysis in MCF-7 and MDA-MB ...
Xiaohong Wang +10 more
doaj +1 more source
The human DNA glycosylases NEIL1 and NEIL3 excise psoralen-induced DNA-DNA cross-links in a four-stranded DNA structure [PDF]
, 2017 Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked ...
A Katafuchi +44 more
core +3 more sources
Biotic elicitor enhanced production of psoralen in suspension cultures of Psoralea corylifolia L. [PDF]
, 2014 Cell cultures of Psoralea corylifolia L. were established from the leaf disk derived callus. The effect of different biotic elicitors prepared from the fungal extract (Aspergillus niger and Penicillium notatum), yeast extract and chitosan with different ...
Ahmed, Syed Abrar +1 more
core +1 more source
Effects of psoralen on the pharmacokinetics of anastrozole in rats
Pharmaceutical Biology, 2018 Context: Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. Objective: This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. Materials and
Yuzhu Zhang +4 more
doaj +1 more source
Photodynamic Therapy of Necrobiosis Lipoidica - A Multicenter Study of 18 Patients [PDF]
, 2008 Background: Necrobiosis lipoidica (NL) is a granulomatous skin disease of unknown origin, and no reliably effective treatment option exists to handle this often disfiguring disease.
Arenberger, P. +4 more
core +1 more source
Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts. [PDF]
PLoS ONE, 2011 Interstrand crosslink (ICL)-inducing agents block the separation of the two DNA strands. They prevent transcription and replication and are used in clinics for the treatment of cancer and skin diseases. Here, we have introduced a single psoralen ICL at a
Cyrille Le Breton +3 more
doaj +1 more source
Frontiers in Chemistry, 2023 Drug-induced liver injury (DILI) is one of the most common causes of a drug being withdrawn, and identifying the culprit drugs and the host factors at risk of causing DILI has become a current challenge. Recent studies have found that immune status plays
Ming-Liang Zhang +41 more
doaj +1 more source
A Perspective on the Use of NB-UVB Phototherapy vs. PUVA Photochemotherapy [PDF]
, 2018 Narrowband UVB (NB-UVB) phototherapy and psoralen-UVA (PUVA) photochemotherapy are widely used phototherapeutic modalities for a range of skin diseases.
Ahmad +119 more
core +3 more sources