Results 41 to 50 of about 18,017 (225)
Synthesis of novel benzofurocoumarin analogues and their anti-proliferative effect on human cancer cell lines [PDF]
, 2012 The synthesis of five new tetracyclic benzofurocoumarin (benzopsoralen) analogues is described. Their inhibitory effects on the growth of three human tumour cell lines (MDA MB 231 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and TCC-SUP (bladder
Campos, Ana M. F. Oliveira +4 more
core +1 more source
Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos +2 more
wiley +1 more source
The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting
Journal of Analytical Methods in Chemistry, 2016 Psoralen and isopsoralen are two isomers and main effective components within Psoralea corylifolia. In order to investigate the salt-processing effect on tissue distribution characters of psoralen and isopsoralen, a sensitive and accurate ultrahigh ...
Gen-hua Zhao +5 more
doaj +1 more source
Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid [PDF]
, 1994 Adenovirus entry into its host cell transiently permeabilizes the cell allowing the coentry of reagents such as DNA. We compare here adenovirus inactivation with β-propiolactone and several psoralen derivatives, seeking reagents that disrupt the viral ...
Birnstiel, Max L. +5 more
core +1 more source
Coumarin Compounds in Callus Cultures
Natural Product Communications, 2014 Coronilla scorpioides (L.) W.D.J. Koch is known for producing several compounds with pharmaceutical interest, such as the hydroxycoumarins umbelliferone, scopoletin and daphnoretin, the dihydrofuranocoumarin marmesin, and the furocoumarin psoralen.
Anna Piovan +2 more
doaj +1 more source
Molecules, 2017 Psoralen and isopsoralen are secondary plant metabolites found in many fruits, vegetables, and medicinal herbs. Psoralen-containing plants (Psoralea corylifolia L.) have been reported to cause hepatotoxicity.
Yue Hai +7 more
doaj +1 more source
Frontiers in Chemistry, 2023 Drug-induced liver injury (DILI) is one of the most common causes of a drug being withdrawn, and identifying the culprit drugs and the host factors at risk of causing DILI has become a current challenge. Recent studies have found that immune status plays
Ming-Liang Zhang +41 more
doaj +1 more source
Efficacy of Narrowband UVB vs. PUVA in Patients with Early-Stage Mycosis Fungoides [PDF]
, 2010 INTRODUCTION: Mycosis fungoides (MF) is a non-Hodgkin's T-cell lymphoma of the skin that often begins as limited patches and plaques with slow progression to systemic involvement.
Apetato, M, Ponte, P, Serrão, V
core +1 more source
JEADV Clinical Practice, EarlyView.ABSTRACT Background Lebrikizumab is approved to treat patients with moderate‐to‐severe atopic dermatitis (AD). Objectives This study evaluated the 16‐week efficacy outcomes of lebrikizumab in adults and adolescents with severe AD in ADvocate trials who would be eligible for treatment based on South Korean reimbursement‐like criteria. Methods This was a
Chong Hyun Won +11 more
wiley +1 more source
Transition on the entropic elasticity of DNA induced by intercalating molecules
, 2007 We use optical tweezers to perform stretching experiments on DNA molecules when interacting with the drugs daunomycin and ethidium bromide, which intercalate the DNA molecule.
Ferreira, M. C. +2 more
core +1 more source