Results 31 to 40 of about 18,017 (225)

DNA-psoralen: single-molecule experiments and first principles calculations

open access: yes, 2010
The authors measure the persistence and contour lengths of DNA-psoralen complexes, as a function of psoralen concentration, for intercalated and crosslinked complexes. In both cases, the persistence length monotonically increases until a certain critical
Alexandre, S. S.   +4 more
core   +1 more source

Effects of psoralen on the pharmacokinetics of anastrozole in rats

open access: yesPharmaceutical Biology, 2018
Context: Psoralen and anastrozole are always used together for breast cancer patients in Chinese clinics. Objective: This study investigates the effects of psoralen on the pharmacokinetics of anastrozole in rats and its potential mechanism. Materials and
Yuzhu Zhang   +4 more
doaj   +1 more source

Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts. [PDF]

open access: yesPLoS ONE, 2011
Interstrand crosslink (ICL)-inducing agents block the separation of the two DNA strands. They prevent transcription and replication and are used in clinics for the treatment of cancer and skin diseases. Here, we have introduced a single psoralen ICL at a
Cyrille Le Breton   +3 more
doaj   +1 more source

The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. [PDF]

open access: yes, 2016
BackgroundPUVA treatment is photochemotherapy for psoriasis that combines psoralen with UVA radiation. Although PUVA is a very effective treatment option for psoriasis, there is an absence of patient resources explaining and demonstrating the process of ...
Abrouk, Michael   +10 more
core   +3 more sources

A theoretical insight into the photophysics of psoralen [PDF]

open access: yes, 2006
Psoralen photophysics has been studied on quantum chemistry grounds using the multiconfigurational second-order perturbation method CASPT2. Absorption and emission spectra of the system have been rationalized by computing the energies and properties of ...
Bonnett R.   +9 more
core   +2 more sources

Ask a pathologist [PDF]

open access: yes, 2017
This article answers the question: Our hospital blood bank has started using platelet additive solution (PAS) platelets and psoralen treated platelets.
Coberly, Emily
core   +1 more source

The Immunogenicity and Properties of a Whole-Cell ETEC Vaccine Inactivated with Psoralen and UVA Light in Comparison to Formalin

open access: yesMicroorganisms, 2023
Inactivated whole-cell vaccines present a full repertoire of antigens to the immune system. Formalin treatment, a standard method for microbial inactivation, can modify or destroy protein antigenic epitopes.
Marlena M. Westcott   +6 more
doaj   +1 more source

Sustainable Microwave‐Enhanced Synthesis of 2‐Substituted Benzofurans From o‐Alkynylanisoles in Acidic Deep Eutectic Solvents

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A microwave‐enhanced sustainable and versatile approach to substituted benzofurans from 2‐alkynylanisoles enabled by an active Brønsted acidic deep eutectic solvent. The research on alternative media for organic transformations remains a highly demanding topic.
Alessandra Gritti   +9 more
wiley   +1 more source

Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]

open access: yes, 1981
Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W.   +3 more
core  

Extracting physical chemistry from mechanics: a new approach to investigate DNA interactions with drugs and proteins in single molecule experiments

open access: yes, 2015
In this review we focus on the idea of establishing connections between the mechanical properties of DNAligand complexes and the physical chemistry of DNA-ligand interactions.
Rocha, M. S.
core   +1 more source

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