Results 41 to 50 of about 18,448 (248)
Microorganisms, 2023 Inactivated whole-cell vaccines present a full repertoire of antigens to the immune system. Formalin treatment, a standard method for microbial inactivation, can modify or destroy protein antigenic epitopes.
Marlena M. Westcott +6 more
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The Effect of Salt-Processed Psoralea corylifolia on Generative Organ Targeting
Journal of Analytical Methods in Chemistry, 2016 Psoralen and isopsoralen are two isomers and main effective components within Psoralea corylifolia. In order to investigate the salt-processing effect on tissue distribution characters of psoralen and isopsoralen, a sensitive and accurate ultrahigh ...
Gen-hua Zhao +5 more
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Molecules, 2017 Psoralen and isopsoralen are secondary plant metabolites found in many fruits, vegetables, and medicinal herbs. Psoralen-containing plants (Psoralea corylifolia L.) have been reported to cause hepatotoxicity.
Yue Hai +7 more
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American Journal of Hematology, EarlyView.ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov +2 more
wiley +1 more source
Efficacy of DNA Intercalator‐Conjugated Triplex‐Forming Oligonucleotide as Anticancer Agent
ChemMedChem, Accepted Article.A triplex‐forming oligonucleotide (TFO) can form a sequence‐specific triple helix via Hoogsteen hydrogen bonding to polypurine tracts within a major groove side of a DNA duplex. Triplex formation can induce a double‐strand break, and this phenomenon at the amplified gene loci can selectively induce the cell death of cancer cells with specific gene ...
Haruki Toyama +5 more
wiley +1 more source
The Association of Psoriasis With Sleep Disorders in a Diverse National Cohort
JEADV Clinical Practice, EarlyView.ABSTRACT Background Higher prevalence of sleep disorders is seen in persons with psoriasis (PsO). However, the extent to which sleep conditions are linked to PsO severity, particularly across diverse populations, remains unknown. Bridging this knowledge gap is vital for developing comprehensive, equitable and personalized care strategies. Objectives We
Michael J. Diaz +6 more
wiley +1 more source
Mycosis Fungoides in Paediatric Patients: A Real‐Life Retrospective Study
JEADV Clinical Practice, EarlyView.Our study represents the largest cohort of children with MF worldwide, providing relevant evidence supporting phototherapy as first‐line treatment, with an overall remission rate of 36.36%. Both topical and systemic therapy also showed favourable outcomes.
Mariana de la Vega +2 more
wiley +1 more source
Journal of Nucleic Acids, 2010 Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We
Rajagopal Krishnan, Dennis H. Oh
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Formulation and evaluation of antipsoriatic gel using natural excipients
Journal of Acute Disease, 2013 Objective: To develop topical gel formulations of Psoralen using natural excipients to minimize the side effects of synthetic drugs. Methods: The Psoralen gel formulations were prepared using different natural gums and polymers.
Raghupatruni Jhansi Laxmi +3 more
doaj +1 more source
Evaluation of S100B serum level as a biomarker of disease activity in vitiligo patients [PDF]
International Journal of Medical Arts, 2019 Background: Vitiligo is a depigmenting disorder characterized by the appearance of circumscribed white macules in the skin. The aetiology of vitiligo is not clear, and although various hypotheses have been proposed.
radwa abd El-Halim +3 more
doaj +1 more source