Results 51 to 60 of about 18,448 (248)

Combinations of Blue and Red LEDs Increase the Morphophysiological Performance and Furanocoumarin Production of Brosimum gaudichaudii Trécul in vitro

Frontiers in Plant Science, 2021
Brosimum gaudichaudii is a plant species with medicinal relevance due to its furanocoumarin accumulation. The accumulation of these compounds in the root promotes predatory extractivism, which threatens the conservation of the species.
Érica Letícia Gomes Costa, Fernanda dos Santos Farnese, Thales Caetano de Oliveira, Márcio Rosa, Arthur Almeida Rodrigues, Erika Crispim Resende, Ana Helena Januario, Fabiano Guimarães Silva   +7 more
doaj   +1 more source

DNA Hanger: Surface‐Minimized Single‐Molecule Immunoassay Platform

Small, EarlyView.
The DNA Hanger platform suspends long DNA molecules biotinylated along their length away from the surface, effectively minimizing nonspecific protein binding. The assay achieves high sensitivity and specificity in single‐molecule FLISA down to subpicomolar levels.
Jincheol Seol, Byungju Kim, Eui‐Sang Yu, Cherlhyun Jeong, Jong‐Bong Lee   +4 more
wiley   +1 more source

miR-488 negatively regulates osteogenic differentiation of bone marrow mesenchymal stem cells induced by psoralen by targeting Runx2

Molecular Medicine Reports, 2019
It has been previously reported that psoralen, one of the active ingredients in Psoralea corylifolia, could induce osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs), suggesting its potential to treat osteoporosis.
Yong-quan Huang, Qiuke Hou, Haitao Su, Dongfeng Chen, Yiwen Luo, Tao Jiang   +5 more
semanticscholar   +1 more source

Pruritus Is an Indicator for Quality of Life in Cutaneous T‐Cell Lymphoma

The Journal of Dermatology, EarlyView.
ABSTRACT In cutaneous T‐cell lymphoma (CTCL), chronic pruritus affects up to 94% of patients as a leading factor reducing quality of life (QoL). Traditional antipruritic medication does not show sufficient relief. Partly due to a lack of therapeutic options, pruritus is rarely assessed in a standardized manner within routine clinical practice.
Andrea Roggo, Yves Wüest, Reinhard Dummer, Egle Ramelyte   +3 more
wiley   +1 more source

Crystal structure of bergapten: a photomutagenic and photobiologically active furanocoumarin

Acta Crystallographica Section E: Crystallographic Communications, 2016
The title compound, C12H8O4, is a furanocoumarin [systematic name: 4-methoxy-7H-furo[3,2-g]chromen-7-one], which was isolated from the Indian herb T. stictocarpum. The molecule is almost planar with an r.m.s.
A. K. Bauri, Sabine Foro, Quynh Nguyen Nhu Do   +2 more
doaj   +1 more source

Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae

Genetics and Molecular Biology, 2012
Eukaryotic cells have developed mechanisms to prevent genomic instability, such as DNA damage detection and repair, control of cell cycle progression and cell death induction.
Lavínia Almeida Cruz, Temenouga Nikolova Guecheva, Diego Bonato, João Antônio Pêgas Henriques   +3 more
doaj   +1 more source

European Guideline (EuroGuiDerm) on atopic eczema: Living update

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg, M. Kinberger, B. Arents, N. Aszodi, S. Barbarot, T. Bieber, H. A. Brough, P. Calzavara‐Pinton, S. Christen‐Zaech, M. Deleuran, M. Dittmann, N. Fosse, K. Gáspár, L. A. A. Gerbens, U. Gieler, G. Girolomoni, S. Gregoriou, S. Holland, C. G. Mortz, A. Nast, U. Nygaard, E. M. Rehbinder, J. Ring, M. Rossi, E. Serra‐Baldrich, D. Simon, Z. Z. Szalai, J. C. Szepietowski, A. Torrelo, T. Werfel, R. N. Werner, C. Flohr   +31 more
wiley   +1 more source

Regorafenib‐Induced Hand‐Foot Skin Reaction in an Adolescent

Pediatric Dermatology, EarlyView.
ABSTRACT Regorafenib is a multikinase inhibitor commonly used in the management of hepatocellular carcinoma, gastrointestinal stromal tumors (GIST), and colorectal cancer. It is also used off‐label for progressive or metastatic osteosarcoma, which is the most common primary bone malignancy in children and adolescents.
Kiera Murphy, Bansri Patel, Shantelle Griffith, Thomas N. Helm   +3 more
wiley   +1 more source

Effect of psoralen on bone formation [PDF]

Journal of Orthopaedic Research, 2010
AbstractTo compare the amount of new bone and bone cells produced by psoralen in collagen matrix to that produced by collagen matrix in vivo. Eighteen bone defects, 5 mm by 10 mm were created in the parietal bone of nine New Zealand White rabbits. Six defects were grafted with psoralen mixed with collagen matrix.
Wong, RWK, Rabie, ABM
openaire   +4 more sources

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source