Results 51 to 60 of about 19,791 (256)
This review summarizes recent progress in chalcogen (S, Se, Te)‐incorporated photosensitizers and photothermal agent design. It explores synthetic strategies, spectroscopic and computational characterization, and in vitro/in vivo evaluations, showcasing the potential of these compounds for photodynamic and photothermal therapies.
Subhrakant Jena+3 more
wiley +1 more source
Psoralen and angelicin are two effective compounds isolated from psoraleae, a traditional Chinese medicine. They have a wide range of applications for bone disease treatment and immune modulation. In this study, we explored their new applications for the
Xiaotian Li+19 more
doaj +1 more source
Transition on the entropic elasticity of DNA induced by intercalating molecules
We use optical tweezers to perform stretching experiments on DNA molecules when interacting with the drugs daunomycin and ethidium bromide, which intercalate the DNA molecule.
Ferreira, M. C.+2 more
core +1 more source
Genome-wide determination of drug localization [PDF]
A vast number of small-molecule ligands, including therapeutic drugs under development and in clinical use, elicit their effects by binding specific proteins associated with the genome.
Anders, Lars+11 more
core +1 more source
The Association of Psoriasis With Sleep Disorders in a Diverse National Cohort
ABSTRACT Background Higher prevalence of sleep disorders is seen in persons with psoriasis (PsO). However, the extent to which sleep conditions are linked to PsO severity, particularly across diverse populations, remains unknown. Bridging this knowledge gap is vital for developing comprehensive, equitable and personalized care strategies. Objectives We
Michael J. Diaz+6 more
wiley +1 more source
Mycosis Fungoides in Paediatric Patients: A Real‐Life Retrospective Study
Our study represents the largest cohort of children with MF worldwide, providing relevant evidence supporting phototherapy as first‐line treatment, with an overall remission rate of 36.36%. Both topical and systemic therapy also showed favourable outcomes.
Mariana de la Vega+2 more
wiley +1 more source
Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We
Rajagopal Krishnan, Dennis H. Oh
doaj +1 more source
Formulation and evaluation of antipsoriatic gel using natural excipients
Objective: To develop topical gel formulations of Psoralen using natural excipients to minimize the side effects of synthetic drugs. Methods: The Psoralen gel formulations were prepared using different natural gums and polymers.
Raghupatruni Jhansi Laxmi+3 more
doaj +1 more source
Evaluation of S100B serum level as a biomarker of disease activity in vitiligo patients [PDF]
Background: Vitiligo is a depigmenting disorder characterized by the appearance of circumscribed white macules in the skin. The aetiology of vitiligo is not clear, and although various hypotheses have been proposed.
radwa abd El-Halim+3 more
doaj +1 more source
Brosimum gaudichaudii is a plant species with medicinal relevance due to its furanocoumarin accumulation. The accumulation of these compounds in the root promotes predatory extractivism, which threatens the conservation of the species.
Érica Letícia Gomes Costa+7 more
doaj +1 more source