Results 51 to 60 of about 21,032 (282)

Structural Determinants of Photoreactivity of Triplex Forming Oligonucleotides Conjugated to Psoralens

Journal of Nucleic Acids, 2010
Triplex-forming oligonucleotides (TFOs) with both DNA and 2′-O-methyl RNA backbones can direct psoralen photoadducts to specific DNA sequences. However, the functional consequences of these differing structures on psoralen photoreactivity are unknown. We
Rajagopal Krishnan, Dennis H. Oh
doaj   +1 more source

Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae

Genetics and Molecular Biology, 2012
Eukaryotic cells have developed mechanisms to prevent genomic instability, such as DNA damage detection and repair, control of cell cycle progression and cell death induction.
Lavínia Almeida Cruz, Temenouga Nikolova Guecheva, Diego Bonato, João Antônio Pêgas Henriques   +3 more
doaj   +1 more source

Combinations of Blue and Red LEDs Increase the Morphophysiological Performance and Furanocoumarin Production of Brosimum gaudichaudii Trécul in vitro

Frontiers in Plant Science, 2021
Brosimum gaudichaudii is a plant species with medicinal relevance due to its furanocoumarin accumulation. The accumulation of these compounds in the root promotes predatory extractivism, which threatens the conservation of the species.
Érica Letícia Gomes Costa, Fernanda dos Santos Farnese, Thales Caetano de Oliveira, Márcio Rosa, Arthur Almeida Rodrigues, Erika Crispim Resende, Ana Helena Januario, Fabiano Guimarães Silva   +7 more
doaj   +1 more source

439 Psoralen plus ultraviolet A for acute cutaneous graft versus host disease [PDF]

, 2023
A. Martinez, Z. Thuesmunn, D.S. Hippe, M.M. Shinohara   +3 more
openalex   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Crystal structure of bergapten: a photomutagenic and photobiologically active furanocoumarin

Acta Crystallographica Section E: Crystallographic Communications, 2016
The title compound, C12H8O4, is a furanocoumarin [systematic name: 4-methoxy-7H-furo[3,2-g]chromen-7-one], which was isolated from the Indian herb T. stictocarpum. The molecule is almost planar with an r.m.s.
A. K. Bauri, Sabine Foro, Quynh Nguyen Nhu Do   +2 more
doaj   +1 more source

Evaluation of S100B serum level as a biomarker of disease activity in vitiligo patients [PDF]

International Journal of Medical Arts, 2019
Background: Vitiligo is a depigmenting disorder characterized by the appearance of circumscribed white macules in the skin. The aetiology of vitiligo is not clear, and although various hypotheses have been proposed.
radwa abd El-Halim, Hasan Mohamed, Ibrahim Fouda, Hesham Abd El-Samee   +3 more
doaj   +1 more source

The human DNA glycosylases NEIL1 and NEIL3 excise psoralen-induced DNA-DNA cross-links in a four-stranded DNA structure [PDF]

, 2017
Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked ...
A Katafuchi, A Mazumder, AM Maxam, B Houten Van, BH Johnston, CG Neurauter, D Klein Douwel, DO Zharkov, DR Semlow, DT Long, GD Cimino, I Khutsishvili, IG Minko, J Huang, J Zhang, J Zhang, K Nojima, KR Kumaresan, L Wiederhold, LJ Niedernhofer, M Budzowska, M Liu, M Liu, M Liu, M Raschle, ML Dodson, ML Dronkert, ML Hegde, MR Hodskinson, PJ McHugh, PJ McHugh, RA Rieger, RP Cunningham, RS Cole, S Couve, S Couve-Privat, S Sharma, SZ Krokeide, TK Hazra, U Roy, V Bailly, V Bandaru, W Xu, X Shen, Z Yang   +44 more
core   +4 more sources

T‐Shaped 8‐Aryl(ethynyl)‐Substituted Psoralens With Tunable Charge‐Transfer Absorption

European Journal of Organic Chemistry, EarlyView.
Starting from 8‐methoxypsoralen, new 8‐arylated and 8‐alkynylated psoralen derivatives are accessible by cross‐coupling. These T‐shaped π‐expanded chromophores are luminescent and photophysics reveal a highly polar excited state with tunable charge‐transfer character.
Lena T. Leusch, Thomas J. J. Müller
wiley   +1 more source

Laser Microirradiation of Chinese Hamster Cells at Wavelength 365 nm [PDF]

, 1981
Cells of a V79 subline of the Chinese hamster were microirradiated at wavelength 365 nm in the presence of the psoralen derivative, trioxsalen. Microirradiation was accomplished by a pulsed argon laser microbeam either in anaphase or in interphase 3 hr ...
Berns, Michael W., Cremer, Christoph, Cremer, Thomas, Peterson, S. P.   +3 more
core