Results 61 to 70 of about 19,791 (256)

Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid [PDF]

, 1994
Adenovirus entry into its host cell transiently permeabilizes the cell allowing the coentry of reagents such as DNA. We compare here adenovirus inactivation with β-propiolactone and several psoralen derivatives, seeking reagents that disrupt the viral ...
Birnstiel, Max L., Cotten, Matt, Kursa, Malgorzata, Maass, Gerd, Saltik, Mediyha, Wagner, Ernst   +5 more
core   +1 more source

European Guideline (EuroGuiDerm) on atopic eczema: Living update

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg, M. Kinberger, B. Arents, N. Aszodi, S. Barbarot, T. Bieber, H. A. Brough, P. Calzavara‐Pinton, S. Christen‐Zaech, M. Deleuran, M. Dittmann, N. Fosse, K. Gáspár, L. A. A. Gerbens, U. Gieler, G. Girolomoni, S. Gregoriou, S. Holland, C. G. Mortz, A. Nast, U. Nygaard, E. M. Rehbinder, J. Ring, M. Rossi, E. Serra‐Baldrich, D. Simon, Z. Z. Szalai, J. C. Szepietowski, A. Torrelo, T. Werfel, R. N. Werner, C. Flohr   +31 more
wiley   +1 more source

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. [PDF]

, 1992
We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an adenovirus-polylysine-reporter-gene complex that transferred ...
Birnstiel, Max L., Cotten, Matt, Curiel, David T., Kirlappos, Helen, Mechtler, Karl, Wagner, Ernst, Zatloukal, Kurt   +6 more
core   +1 more source

Regorafenib‐Induced Hand‐Foot Skin Reaction in an Adolescent

Pediatric Dermatology, EarlyView.
ABSTRACT Regorafenib is a multikinase inhibitor commonly used in the management of hepatocellular carcinoma, gastrointestinal stromal tumors (GIST), and colorectal cancer. It is also used off‐label for progressive or metastatic osteosarcoma, which is the most common primary bone malignancy in children and adolescents.
Kiera Murphy, Bansri Patel, Shantelle Griffith, Thomas N. Helm   +3 more
wiley   +1 more source

Crystal structure of bergapten: a photomutagenic and photobiologically active furanocoumarin

Acta Crystallographica Section E: Crystallographic Communications, 2016
The title compound, C12H8O4, is a furanocoumarin [systematic name: 4-methoxy-7H-furo[3,2-g]chromen-7-one], which was isolated from the Indian herb T. stictocarpum. The molecule is almost planar with an r.m.s.
A. K. Bauri, Sabine Foro, Quynh Nguyen Nhu Do   +2 more
doaj   +1 more source

The Role of Sex Hormones in Cartilaginous Tissues: A Scoping Review

JOR SPINE, Volume 8, Issue 2, June 2025.
The role of sex hormones within cartilaginous tissues remains poorly understood. To address this, we assembled and summarized the available literature regarding the effects of sex hormones in the intervertebral disc, temporomandibular joint, and articular cartilage.
Jeffrey L. Hutchinson, Amalie J. Hutchinson, Joy Feng, Cheryle A. Séguin   +3 more
wiley   +1 more source

Relationships between chromatin remodeling and DNA damage repair induced by 8-methoxypsoralen and UVA in yeast Saccharomyces cerevisiae

Genetics and Molecular Biology, 2012
Eukaryotic cells have developed mechanisms to prevent genomic instability, such as DNA damage detection and repair, control of cell cycle progression and cell death induction.
Lavínia Almeida Cruz, Temenouga Nikolova Guecheva, Diego Bonato, João Antônio Pêgas Henriques   +3 more
doaj   +1 more source

Evolution of substrate recognition sites (SRSs) in cytochromes P450 from Apiaceae exemplified by the CYP71AJ subfamily [PDF]

, 2015
Background Large proliferations of cytochrome P450 encoding genes resulting from gene duplications can be termed as ‘blooms’, providing genetic material for the genesis and evolution of biosynthetic pathways.
Bourgaud, Frederic, Drew, Damian, Dueholm, Bjørn, Hehn, Alain, Kamo, Tsunashi, Krieger, Celia, Olry, Alexandre, Simonsen, Henrik Toft, Taboureau, Olivier, Weitzel, Corinna   +9 more
core   +4 more sources

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]

, 1986
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Barranco, Brenner, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, González-Fernández, Hens, Kihlman, Kihlman, Kihlman, Kihlman, Lau, Lehmann, Moreno, Nilsson, Painter, Painter, Raith, Rappold, Roberts, Schardin, Sedgwick, Setlow, Stack, Steward, Tatsumi, Tobey, Tomulin, Zorn, Zorn   +42 more
core   +1 more source

Effect of psoralen on bone formation [PDF]

Journal of Orthopaedic Research, 2010
AbstractTo compare the amount of new bone and bone cells produced by psoralen in collagen matrix to that produced by collagen matrix in vivo. Eighteen bone defects, 5 mm by 10 mm were created in the parietal bone of nine New Zealand White rabbits. Six defects were grafted with psoralen mixed with collagen matrix.
Wong, RWK, Rabie, ABM
openaire   +4 more sources