Results 131 to 140 of about 161,729 (326)
The Journal of Clinical Pharmacology, EarlyView.Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley +1 more source
Analysis of hope level and its influencing factors in patients with decompensated cirrhosis
Nursing Open, Volume 10, Issue 2, Page 623-629, February 2023., 2023 Abstract Aim The aim of this study was to examine hope level and its influencing factors in patients with decompensated liver cirrhosis. Design A prospective observational study. Methods We selected 93 patients with decompensated liver cirrhosis from a Chinese university hospital based on the inclusion and exclusion criteria.
Yuanyuan Zhang +6 more
wiley +1 more source
Nursing Open, Volume 10, Issue 2, Page 649-657, February 2023., 2023 Abstract Aim We analysed whether immediate skin‐to‐skin contact between the healthy newborn and the mother after a caesarean section has a modulatory role on postpartum haemorrhage and uterine contraction. Design Unblinded, randomized clinical trial, simple random sampling, conducted in women undergoing caesarean sections.
José Miguel Pérez‐Jiménez +4 more
wiley +1 more source
Clinical and Translational MedicineIntroduction Tyrosine kinase 2 (TYK2)‐dependent cytokine signalling is integral to the pathogenesis of psoriasis. While BMS‐986165, a highly selective TYK2 inhibitor, has recently been approved for oral treatment of psoriasis, its therapeutic potential ...
Zhiqin Fang +5 more
doaj +1 more source
Journal of Periodontology, EarlyView.Abstract Background Periodontitis has been linked to various systemic health conditions. This study investigated whether the association between periodontitis and prostate‐specific antigen (PSA) is direct or mediated through intermediary systemic diseases.
Muhammad H. A. Saleh +7 more
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Role of body mass index in outcomes of patients hospitalized with COVID‐19 illness
Obesity Science &Practice, Volume 8, Issue 6, Page 748-756, December 2022., 2022 Abstract Background Since the start of coronavirus disease 2019 (COVID‐19) pandemic, several studies have linked obesity with severity of illness as well as mortality in patients with COVID‐19. Outcomes of patients with overweight or obesity, who develop critical illness, have been studied extensively over the past decade where the studies have shown ...
Maleeha Zahid +8 more
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Genital Crohn's disease in pediatrics and genetic associations
JPGN Reports, EarlyView.Abstract Genital edema is a rare presentation of Crohn's disease (CD), also known as metastatic CD (MCD). This may precede, co‐occur with, or follow gastrointestinal symptoms and present a diagnostic challenge. We aimed to characterize the features, clinical courses, pathogenesis, and outcomes of patients with MCD to increase understanding and promote ...
Erica Chang +5 more
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Phytochemical Analysis, Volume 33, Issue 8, Page 1257-1265, December 2022., 2022 Abstract Introduction There are several cannabidiol (CBD) transdermal patches available on the market. However, none are FDA‐approved. Furthermore, not much evidence has been published about CBD release and skin permeation from such patches, so the effectiveness and reliability remain unclear. Objectives We aimed to develop a method to determine the in
Liyun Yu +4 more
wiley +1 more source