Results 131 to 140 of about 272,684 (347)

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

open access: yesExploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang   +4 more
wiley   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

open access: yesExploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu   +5 more
wiley   +1 more source

Association between periodontitis severity and prostate‐specific antigen levels using the NHANES data

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis has been linked to various systemic health conditions. This study investigated whether the association between periodontitis and prostate‐specific antigen (PSA) is direct or mediated through intermediary systemic diseases.
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

Associations of exposure to acrylamide and glycidamide with psoriasis among adults: Findings from a population-based study

open access: yesEcotoxicology and Environmental Safety
Acrylamide (AA), a hazardous chemical prevalent in the environment and human diet, and its metabolite glycidamide (GA) are suspected contributors to psoriasis.
Rui Ma   +7 more
doaj  

Apremilast Decreased Proinflammatory Cytokines and Subsequently Increased Inhibitory ones in Psoriasis: A Prospective Cohort Study

open access: yesActa Dermato-Venereologica
is missing (Short communication)
Takemichi Fukasawa   +4 more
doaj   +1 more source

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine   +24 more
wiley   +1 more source

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