Results 121 to 130 of about 166,859 (297)

Effectiveness of baricitinib in acquired reactive perforating collagenosis: a case report

Frontiers in Immunology
BackgroundAcquired reactive perforating collagenosis (ARPC) poses a clinical challenge with an unclear pathogenesis. This disease has been frequently proven resistant to immunosuppressive treatments, significantly affecting the quality of life of ...
Jianfeng Zheng, Jianfeng Zheng, Yangfeng Ding, Yangfeng Ding, Yuanyuan Chen, Yuanyuan Chen, Yuling Shi, Yuling Shi, Yunlu Gao, Yunlu Gao   +9 more
doaj   +1 more source

The pharmacological treatment of psoriasis

, 2022
Psoriasis is a chronic, multisystemic, autoimmune disease with an unknown etiology that can severely affect patients’ lives. Chronic inflammation is the hallmark of the disease, with treatments aimed at decreasing the immune response either locally or ...
Tzikinovsky, Yair
core  

Association of Childhood Acute Leukemia With Autoimmune Diseases

International Journal of Cancer, EarlyView.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka, Julia Ventelä, Anssi Auvinen, Olli Lohi, Atte Nikkilä   +4 more
wiley   +1 more source

Outcomes and risk factors of COVID-19 in patients with bullous pemphigoid: a cross-sectional study

Frontiers in Immunology
BackgroundThe outcomes of coronavirus disease 2019 (COVID-19) in patients with bullous pemphigoid (BP) remain insufficiently understood. This study aimed to evaluate the impact of COVID-19 on BP patients and identify factors influencing the risk and ...
Yuexin Zhang, Yuexin Zhang, Dawei Huang, Dawei Huang, Yuling Shi, Yuling Shi, Yangfeng Ding, Yangfeng Ding, Yunlu Gao, Yunlu Gao   +9 more
doaj   +1 more source

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

Association between periodontitis and oral health–related quality of life in patients with systemic conditions: A meta‐analysis

Journal of Periodontology, EarlyView.
Abstract Background The objective of this systematic review is to evaluate whether periodontitis is associated with impaired oral health–related quality of life (OHRQoL) in adults with systemic conditions. Methods Five databases were searched to identify observational studies that tested the association between periodontitis (diagnosed by clinical ...
Rafael Vargas Bortolaso, Catiusse Crestani Del' Agnese, Leandro Machado Oliveira, Patricia A. Miguez, Fabricio Batistin Zanatta, Raquel Pippi Antoniazzi   +5 more
wiley   +1 more source

The needle study: Machine learning as a new method for case‐finding in celiac disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite a well‐defined diagnostic work‐up, uncertainties persist regarding celiac disease (CeD) detection strategies in the general population. Machine learning (ML) algorithms offer promise in aiding medical decision‐making on clinical data.
Chiara Maria Trovato, Monica Montuori, Maria Ludovica Costanzo, Giusy Russo, Cosimo Ruggiero, Danila Volpe, Francesca Ferretti, Antonella Diamanti, Carlo Ciliberto, Salvatore Oliva   +9 more
wiley   +1 more source