Results 141 to 150 of about 166,859 (297)

LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activation

Cell Discovery
The role of CD8+ tissue-resident memory T (CD8+ TRM) in inflammation is well established. However, the mechanisms by which CD8+ TRM cells are activated in tissues have remained elusive.
Rundong Jiang, Zhiqin Fang, Yutong Wang, Bo Huang, Junkun Liu, Lam C. Tsoi, Rachael Bogle, Zongbo Zhang, Yehong Kuang, Xin Li, Liang Dong, Liping Jin, Johann E. Gudjonsson, Mingzhu Yin, Xiang Chen   +14 more
doaj   +1 more source

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source

Costo-efectividad de tratamientos utilizados en los pacientes con psoriasis moderada y severa, en el Centro de la Piel en Quito-Ecuador (2005-2008)

, 2008
La Psoriasis es una enfermedad inflamatoria crónica de la piel, no contagiosa, que produce lesiones tipo placa eritemato-escamosa, con una amplia variabilidad clínica y evolutiva.
Domnick, Jaime Werner
core   +1 more source

G2‐PASE: A Novel, Rapid, and Reliable Measure of Plaque Psoriasis Severity

JEADV Clinical Practice, EarlyView.
ABSTRACT Background The Psoriasis Area and Severity Index (PASI), a composite measure of plaque psoriasis disease severity, is commonly used to determine treatment eligibility and response, but is time consuming for every‐day clinical use. The Gulliver‐Gestalt‐Psoriasis Area Severity Estimate (G2‐PASE) was developed to approximate PASI scores using ...
Wayne P. Gulliver, Wayne Langholff, Lyn Guenther, Vimal H. Prajapati, Julien Ringuet, Om Prakash Yadav, Susanne R. Gulliver, Steve Fakharzadeh, Kim Parnell Lafferty, Nastaran Abbarin, Robert Gniadecki   +10 more
wiley   +1 more source

Managing Skin Diseases During Pregnancy: Treatment Discontinuation, Concerns and Physician Counselling

JEADV Clinical Practice, EarlyView.
Physiological changes during pregnancy can trigger or worsen dermatological conditions, yet evidence‐based guidance for safe management remains limited. In a cross‐sectional survey of 273 pregnant women, 33.7% reported having a skin disease, and 56% experienced worsening of symptoms.
Frederikke Seeberg, Anne Sofie Frølunde, Mette Deleuran, Line Kolding, Christian Vestergaard   +4 more
wiley   +1 more source

Imiquimod-induced Psoriasis-like Mouse Model

, 2012
Psoriasis is a chronic inflammatory skin disease affecting 1-2% of the population. The pathogenesis of psoriasis is not fully understood, but recent progress in studying its complex mechanisms revealed that crosstalk among T cells, epidermal ...
이민걸
core  

Prevalence of Colonization, Association With Disease Stage and Effect of Eradication of Staphylococcus aureus in Cutaneous T‐Cell Lymphoma: A Systematic Review and Meta‐Analysis

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Cutaneous T‐cell lymphoma (CTCL) is a rare and heterogeneous group of skin‐homing lymphomas with a largely unknown pathogenesis. Staphylococcus aureus (S. aureus) colonization has been implicated in exacerbating CTCL, particularly in advanced stages. Objectives This study assessed the prevalence of S.
Ida Lind Holm, Sarah Søltoft Rasmussen, Somaia Naassan, Misbah N. Ghazanfar, Kenneth Thomsen, Rikke Bech, Lise M. Lindahl, Maria Kamstrup, Simon Francis Thomsen, Zarqa Ali   +9 more
wiley   +1 more source

Glucagon-like peptide-1 receptor agonist therapy in patients with psoriasis and diabetes mellitus type 2.

reservedIntroduction: Psoriasis is a chronic inflammatory skin disease often associated with type 2 diabetes and other metabolic disorders. GLP-1 receptor agonists (GLP-1 RAs), used for glycemic control and weight management in diabetes, have shown ...
MIOSO, GUIDO
core  

A Belgian consensus on the definition of a treat-to-target outcome set in psoriasis management

, 2019
: Objective Treat-to-target (T2T) is an algorithm to reach a predefined outcome. Here, we define a T2T outcome for moderate-to-severe psoriasis vulgaris.
Bonardeaux, Chantal, Hillary, T., Segaert, S., Lanssens, Sven, Temmerman, Linda, Henno, Audrey, Vandaele, Mark, Boonen, Hugo, Stockman, Annelies, Vermeersch, Karen, Grine, L., Ghislain, P. -D., Lambert, Julien, de la Brassinne, M., Nikkels F., Arjen, Willaert, F., Suys, Erwin, Benhadou, Farida   +17 more
core  

Residual Disease in Adult Psoriasis‐Treated Patients: Frequency, Clinical Aspects, and Management. A Survey Among Dermatologists

JEADV Clinical Practice, EarlyView.
Abstract Background In moderate‐to‐severe psoriasis, residual lesions can be defined as “psoriasis lesions that persist despite well‐managed treatment, and which do not necessarily justify intensification or a change in treatment.” Residual lesions are accepted by guidelines and clinical trials.
Emmanuel Mahé, Nathalie Quiles‐tsimaratos, Bruno Halioua, Antoine Delpuech, Charles Taieb   +4 more
wiley   +1 more source