ABSTRACT Vitiligo, a common and chronic depigmentation disorder, significantly impacts patients' quality of life and exerts a substantial economic burden. The deleterious impact of vitiligo can be exacerbated by comorbid conditions, including psychiatric and autoimmune conditions.
Naoki Oiso +9 more
wiley +1 more source
The Definition of Psoriasis Severity and Treatment Target of Psoriasis: Korean Expert Consensus Using the Modified Delphi Method. [PDF]
Bang CH +8 more
europepmc +1 more source
Effect of Anti‐IL‐23 and Anti‐IL‐17 Therapy on Darier Disease: A Case Series
ABSTRACT Darier disease is a rare ATP2A2‐related genodermatosis for which therapeutic options remain limited, as acitretin is often constrained by toxicity and teratogenicity. In this retrospective real‐world case series of eight patients, anti‐IL‐17 therapy showed a more consistent early signal of clinical benefit than anti‐IL‐23 therapy, with greater
Maione Vincenzo +6 more
wiley +1 more source
Comparative Efficacy of Interleukin Inhibitors and JAK Inhibitors in Moderate to Severe Plaque Psoriasis. [PDF]
Daily A +4 more
europepmc +1 more source
The Evaluation of the Clinical Effectiveness and Safety of Biologic Therapies in Psoriasis-Real-World Evidence up to 64 Weeks of Therapy. [PDF]
Lemiesz P +3 more
europepmc +1 more source
Exploring the role of neuro-immune modulation for psoriasis management: a narrative review of existing evidence and future therapies. [PDF]
Savic D, Serafini RA, Ning S.
europepmc +1 more source
Psoriasis and chronic kidney disease: a systemic inflammatory link and a practical kidney assessment pathway. [PDF]
Almeida-Silva G +6 more
europepmc +1 more source
Cobalt chloride (CoCl2) and cobalt nanoparticles (CoNPs) induce a shared, severity‐dependent inflammatory response in cobalt‐sensitized skin characterized by activation of interferon signaling, inflammatory pathways (TNF/NF‐κβ, IL6‐STAT3), apoptosis/UPR, cell cycle programs, and glycolysis.
Paulina Werner +8 more
wiley +1 more source
Optogenetic Dissection of Sensory Neuron-Macrophage Interactions in Psoriasiform Skin Inflammation: Advances Based on In Vivo Calcium Imaging Techniques. [PDF]
Zheng P, Chen L.
europepmc +1 more source
Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally +6 more
wiley +1 more source

