Mechanisms and therapeutic targets in psoriatic arthritis: balancing inflammatory bone resorption and bone formation. Abstract Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by diverse clinical manifestations. Of particular concern, osteopenia and osteoporosis are prevalent in 45.27% and 12.94% of PsA patients, respectively ...
Yingchao Sun+3 more
wiley +1 more source
Comparative analysis of cutaneous features of psoriasis in acute and chronic imiquimod-induced mouse models. [PDF]
Fraillon E+11 more
europepmc +1 more source
Cryomicroneedle Arrays for Biotherapeutics Delivery
CryoMNs for biotherapeutic delivery to treat various diseases. CryoMNs: cryomicroneedles. Biotherapy offers a promising approach for treating a variety of diseases. However, the lack of advanced delivery systems remains a significant barrier to improve the efficacy, safety, and cost‐effectiveness of biotherapeutics.
Chunli Yang+9 more
wiley +1 more source
Long Non-Coding RNAs in Psoriasis and Cutaneous Squamous Cell Carcinoma. [PDF]
Trufin II+4 more
europepmc +1 more source
ABSTRACT Background and Aims The impact of dietary sugar intake on the risk of developing inflammatory bowel disease is unclear, with inconsistent findings across studies. The aim of this systematic review and meta‐analysis was to clarify how sugar consumption contributes to the risk of developing inflammatory bowel disease (IBD) using the most ...
Isha Maniyar+8 more
wiley +1 more source
Predicting abnormal epicardial adipose tissue in psoriasis patients by integrating radiomics from non-contrast chest CT with serological biomarkers. [PDF]
Han R, Hou J, Xia P, Xing Y, Liu W.
europepmc +1 more source
Effectiveness and Safety of Advanced Dual‐Targeted Therapy in Refractory Perianal Crohn's Disease
ABSTRACT Introduction Perianal Crohn's disease (CD) remains challenging to treat despite the increasing number of advanced therapies. Advanced dual‐targeted therapy has emerged as a new treatment option in CD, but no data are available for perianal CD. The aim of this study was to evaluate the effectiveness and safety of advanced dual‐targeted therapy ...
Nadia Fathallah+9 more
wiley +1 more source
Disease severity and demographic factors in relation to subjective well being among syrian psoriasis patients. [PDF]
Martini N+7 more
europepmc +1 more source
ABSTRACT Background and Aims The relationship between gut microbiota and biological treatment response in inflammatory bowel disease (IBD) remains incompletely understood. We sought to characterize microbial signatures associated with clinical remission and develop a prediction model for clinical remission. Methods We analyzed 16 S rRNA gene sequencing
Qingyang Zheng+10 more
wiley +1 more source
Comprehensive analysis of pyroptosis-related genes in psoriasis and targeted gene editing of CASP1 and CASP5 using lipid nanoparticles to alleviate skin inflammation. [PDF]
Xu G, Ma G, Sun J, Yu X, Sun J, Gao B.
europepmc +1 more source