Results 61 to 70 of about 293,751 (369)
Scientific Reports, 2023 To quantify the pooled rate and risk ratio of seroconversion following the uncomplete, complete, or booster dose of COVID-19 vaccines in patients living with HIV.
Qian Zhou +5 more
doaj +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry +2 more
wiley +1 more source
Nanoparticle‐Mediated Targeted Protein Degradation: An Emerging Therapeutics Technology
Angewandte Chemie, EarlyView.Targeted protein degradation (TPD) has emerged as a powerful therapeutic approach, with numerous candidates molecules now advancing into clinical development. Recent innovations have incorporated nanoparticles to facilitate and enhance these degradation processes, yielding synergistic effects.
Andrew G. Baker +3 more
wiley +2 more sources
NOS2-derived low levels of NO drive psoriasis pathogenesis
Cell Death and DiseasePsoriasis is an IL-23/Th17-mediated skin disorder with a strong genetic predisposition. The impact of its susceptibility gene nitric oxide synthase 2 (NOS2) remains unknown.
Ines Köhler +4 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective We aimed to assess whether high‐sensitivity C‐reactive protein (hsCRP) levels could predict the development of psoriatic arthritis (PsA) in patients with psoriasis. Methods We analyzed data from a prospective cohort of patients with psoriasis without PsA at enrollment.
Lihi Eder +5 more
wiley +1 more source
Immune-mediated inflammation promotes subclinical atherosclerosis in recent-onset psoriatic arthritis patients without conventional cardiovascular risk factors [PDF]
, 2018 Studies on the inflammatory burden in recent-onset psoriatic arthritis (PsA) patients without conventional cardiovascular risk factors (CVRFs) are not available.
Capani, Francisco +8 more
core +1 more source
Psoriasis Severity Assessment with a Similarity-Clustering Machine Learning Approach Reduces Intra- and Inter-observation variation [PDF]
arXiv, 2020 Psoriasis is a complex disease with many variations in genotype and phenotype. General advancements in medicine has further complicated both assessments and treatment for both physicians and dermatologist alike. Even with all of our technological progress we still primarily use the assessment tool Psoriasis Area and Severity Index (PASI) for severity ...
arxiv
Data-Driven Logistic Regression Ensembles With Applications in Genomics [PDF]
arXiv, 2021 Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker identification.
arxiv
Key Trends and Insights in Smart Polymeric Skin Wearable Patches
Advanced Engineering Materials, EarlyView.Intelligent polymers, which respond to various physical and biological stimuli, are explored for the development of skin wearable patches in biomedical applications. Smart polymers, also known as intelligent or stimuli‐responsive polymers, play a crucial role in the development of advanced wearable patches due to their versatility and softness.
Sergio J. Peñas‐Núñez +2 more
wiley +1 more source
Frontiers in Pharmacology, 2021 Psoriasis is an immune-mediated chronic inflammatory skin disease primarily mediated by the activation of interleukin (IL)-17-producing T cells. Traditional Chinese Medicine (TCM) represents one of the most effective complementary and alternative ...
Xilin Zhang +21 more
doaj +1 more source