Results 61 to 70 of about 166,859 (297)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Diet and physical exercise in psoriasis: a randomized controlled trial

, 2014
BACKGROUND: Increased body mass index and weight gain are risk factors for psoriasis, and the prevalence of obesity in patients with psoriasis is higher than in the general population. Limited data exist regarding the role of diet in psoriasis.
Pazzaglia M, Veneziano L, NALDI, LUCIANA, Lanzoni A, Conti A, PATRIZI, ANNALISA, Pellacani G, the Psoriasis Emilia Romagna Study Group, Cazzaniga S   +8 more
core   +1 more source

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

Advanced Science, EarlyView.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian, Yanrui Yang, Qiuyu Li, Ying Hu, Qin Hu, Shasha Ran, Siyu Zhou, Xiujuan Yang, Shanshan Li, Qixiong Zhang   +9 more
wiley   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Failure of non-cultured melanocyte–keratinocyte transplantation in periungual vitiligo: A case report

Journal of Dermatology and Dermatologic Surgery, 2015
Background: Vitiligo is a common pigmentary skin disorder, affecting 0.5–1% of world population. It is one of the psychologically devastating skin disorders, which have different medical and surgical modalities of treatment.
Norah Alsubait, Sanjeev Mulekar, Ahmed Al Issa   +2 more
doaj   +1 more source

Childhood psoriasis [PDF]

, 2017
Psoriasis is a long-lasting inflammatory skin disease with an autoimmunological and immunometabolic background. The latest European data indicate that the occurrence of psoriasis in children ranges from 0.7% to 2.1%.
Wojciech Myśliński, Aldona Pietrzak, Daniel Pietrzak, Dorota Krasowska, Dorota Piekarska-Myślińska, Magdalena Borysowicz, Mateusz Socha   +6 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Associations of exposure to acrylamide and glycidamide with psoriasis among adults: Findings from a population-based study

Ecotoxicology and Environmental Safety
Acrylamide (AA), a hazardous chemical prevalent in the environment and human diet, and its metabolite glycidamide (GA) are suspected contributors to psoriasis.
Rui Ma, Nan Yang, Hao Mei, Yu Zhuang, Yu Wang, Yuanyuan Wang, Xin Wang, Yuling Shi   +7 more
doaj   +1 more source