Results 71 to 80 of about 116,439 (236)

Patient Experiences with Psoriatic Disease in the USA: Results from the Psoriasis and Beyond Global Study

Drugs - Real World Outcomes
Background Psoriatic disease (PsD) is a chronic, multisystem, inflammatory disorder encompassing psoriasis, psoriatic arthritis (PsA), and their associated comorbidities.
April W. Armstrong, Sicily Mburu, George C. Gondo, Elena Kornyeyeva, Susan Frade, Alexis Ogdie   +5 more
doaj   +1 more source

Positive association between insulin resistance and fatty liver disease in psoriasis: evidence from a cross-sectional study

Frontiers in Immunology
BackgroundFatty liver disease (FLD) is a common comorbidity of psoriasis and is often referred to as non-alcoholic fatty liver disease (NAFLD). However, the role of inflammation or insulin resistance (IR) in FLD is inconclusive. The study aims to explore
Xiaoyuan Zhong, Xiaoyuan Zhong, Dawei Huang, Dawei Huang, Rongfen Chen, Rongfen Chen, Lingling Yao, Lingling Yao, Rui Ma, Rui Ma, Yingyuan Yu, Yingyuan Yu, Yuxiong Jiang, Yuxiong Jiang, Luyang Kong, Luyang Kong, Jiajing Lu, Jiajing Lu, Ying Li, Ying Li, Yuling Shi, Yuling Shi   +21 more
doaj   +1 more source

Dosing Biologic Drugs for Patients With Obesity: One Size Does Not Fit All

Arthritis &Rheumatology, EarlyView.
Stephen J. Balevic, Daniel Gonzalez, Bernd Meibohm   +2 more
wiley   +1 more source

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source

Voclosporin‐induced gingival enlargement: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Drug‐influenced gingival enlargement (DIGE) is a recognized adverse effect of certain medications, particularly immunosuppressants like cyclosporin and tacrolimus. However, there have been no documented cases of DIGE associated with voclosporin, a newer calcineurin inhibitor used primarily to treat lupus nephritis.
Francesca Racca, Jessica M. Greco, Dimitris N. Tatakis   +2 more
wiley   +1 more source

Case Report: Exploring the underlying mechanisms of psoriasis comorbid with sarcoidosis: insights from a case of coexisting immune-related disorders

Frontiers in Immunology
Psoriasis, a chronic inflammatory disease characterized by hyperactivation of the Th1/Th17 axis, is increasingly recognized for its comorbid mechanisms with other immune-related disorders. This article reports a rare case. The case involves a 62-year-old
Yingbao Zhen, Yingbao Zhen, Xinlin Liang, Xinlin Liang, Dawei Huang, Dawei Huang, Yangfeng Ding, Yangfeng Ding, Yuling Shi, Yuling Shi, Qian Yu, Qian Yu   +11 more
doaj   +1 more source

Measuring the Impact of the Substitution of Innovator Biologics With Biosimilars on Uptake and Costs Among Ontario Public Drug Benefit Recipients

Clinical Pharmacology &Therapeutics, EarlyView.
In Ontario, biologics have historically represented a small proportion of public drug claims but a large proportion of spending. Biosimilars, lower cost alternatives to biologics, offer a potential solution to the rising spending on biologics. From March 2023 to January 2024, the Ontario Ministry of Health required public drug program beneficiaries on ...
Anita Iacono, Martin K. H. Ho, Joanna Yang, Tonya Campbell, William Wynne, Dana Shearer, Lene Andersen, Eric Majer, Shaleesa Ledlie, Mina Tadrous, Tara Gomes   +10 more
wiley   +1 more source

Quantification of Age and Sex Ratio Differences between Trial and Target Population for New Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials are essential to understand the benefit‐harm profile of new drugs. Lack of adequate representation in age and sex ratio in clinical trials can result, for example, in higher side effects for underrepresented patients. We quantified differences in age and sex ratios between trial and target populations of new drugs approved by the FDA ...
Miquel Serra‐Burriel, Paul Schlossmacher, Kerstin Noelle Vokinger   +2 more
wiley   +1 more source

Impact of temperature trend-defined seasonality on psoriasis treatment outcomes: a multicenter longitudinal study

Frontiers in Immunology
BackgroundPsoriasis severity and symptoms are widely known to vary seasonally. However, evidence on the impact of seasonality on treatment outcomes is limited, with vague season definitions.
Xinyi Song, Qin Yang, Yuye Wang, Ning Yu
doaj   +1 more source

Recent advances in phototherapy for psoriasis [version 1; referees: 2 approved]

F1000Research, 2016
Phototherapy involves repeated exposure of the skin to ultraviolet light to treat various inflammatory skin conditions such as psoriasis. Recent studies have identified specific immunologic effects of phototherapy that may underlie phototherapy efficacy.
Mio Nakamura, Benjamin Farahnik, Tina Bhutani   +2 more
doaj   +1 more source