Results 111 to 120 of about 106,528 (297)

TAM pathway proteins as novel salivary biomarkers for periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background The identification of molecular biomarkers that help clinicians in early diagnosis is a key focus of periodontal research. The major aim of this cross‐sectional observational study was to assess whether salivary TAM pathway protein levels have the potential to discriminate between periodontally healthy or gingivitis controls and ...
Karina Mendes   +7 more
wiley   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner   +21 more
wiley   +1 more source

Methotrexate toxicity and intolerance in paediatric inflammatory bowel disease: A retrospective cohort study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Methotrexate (MTX) is frequently prescribed in paediatric inflammatory bowel disease (IBD), with routine laboratory monitoring to detect adverse events (AEs), such as hepatotoxicity and myelotoxicity. However, data on the incidence and predictors of these AEs remain limited.
Eva Vermeer   +7 more
wiley   +1 more source

Peripheral blood cytokine levels in paediatric‐onset inflammatory bowel disease: A systematic review and meta‐analysis

open access: yesJPGN Reports, EarlyView.
Abstract Objectives We aimed to summarise findings on blood cytokine levels in patients with paediatric‐onset inflammatory bowel disease (PIBD) compared to healthy controls. Methods This systematic review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta‐Analyses) guidelines and was registered at Prospero (CRD42024579684 ...
Sabine Jansson   +7 more
wiley   +1 more source

Efficacy of omega‐3 fatty acids as a functional food: a multifaceted approach to health reinforcement

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad   +12 more
wiley   +1 more source

SPP1+ TAM Regulates the Metastatic Colonization of CXCR4+ Metastasis‐Associated Tumor Cells by Remodeling the Lymph Node Microenvironment

open access: yesAdvanced Science
Lymph node metastasis, the initial step in distant metastasis, represents a primary contributor to mortality in patients diagnosed with oral squamous cell carcinoma (OSCC).
Liang Dong   +8 more
doaj   +1 more source

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