Results 51 to 60 of about 59,113 (302)

Dissecting the Clinical Heterogeneity and Genotype-Phenotype Correlations of MAPT Mutations: A Systematic Review

Frontiers in Bioscience-Landmark
Background: Microtubule-associated protein tau (MAPT) mutations are one of the main causes of genetic Frontotemporal dementia (FTD) and are characterised by high clinical heterogeneity.
Cristina Villa, Elisa Pellencin, Aurora Romeo, Giorgio Giaccone, Giacomina Rossi, Sara Prioni, Paola Caroppo   +6 more
doaj   +1 more source

Post-Stroke Pneumonia in Real-World Practice: Background, Microbiological Examination, and Treatment

Neurology International, 2023
Post-stroke pneumonia (PSP) has an impact on acute ischemic stroke (AIS). Although predictive scores for PSP have been developed, it is occasionally difficult to predict.
Takayoshi Akimoto, Makoto Hara, Masaki Ishihara, Katsuhiko Ogawa, Hideto Nakajima   +4 more
doaj   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

Progressive Supranuclear Palsy in India: Past, Present, and Future

Annals of Indian Academy of Neurology
Progressive supranuclear palsy (PSP) has emerged as a key area of interest among researchers worldwide, including those in India, who have actively studied the disorder over the past several decades.
Srinivas Raju, Kuldeep Shetty, Lulup Sahoo, Vijayashankar Paramanandam, Jay M Iyer, Suvorit Bowmick, Soaham Desai, Deepika Joshi, Niraj Kumar, Sahil Mehta, Rukmini Mridula Kandadai, Pettarusp Wadia, Atanu Biswas, Divyani Garg, Pankaj Agarwal, Syam Krishnan, Jacky Ganguly, Heli Shah, Mitesh Chandarana, Hrishikesh Kumar, Rupam Borgohain, VL Ramprasad, Prashanth Lingappa Kukkle, PRAI Consortium   +23 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

Advanced Science, EarlyView.
This review summarizes the pathogenic role of mitochondria in diseases and highlights mitochondrial transfer and transplantation as emerging therapeutic strategies. It systematically discusses how nanomaterials are engineered to facilitate these processes, and critically examines the current challenges and future perspectives for their clinical ...
Yuanyuan Su, Zhiyan Gong, Jiao Mu, Lili Huang, Pengfei Yang, Chenli Zhang, Lingshan Zhao, Liling Yang, Jun Deng, Xiaohui Liao   +9 more
wiley   +1 more source

The Burden of Progressive Supranuclear Palsy on Patients, Caregivers, and Healthcare Systems by PSP Phenotype: A Cross-Sectional Study

Frontiers in Neurology, 2022
Progressive supranuclear palsy (PSP) is a rare, relentlessly progressive, ultimately fatal neurodegenerative brain disease. The objective of this study was to assess the burden of PSP on patients, caregivers, and healthcare systems by PSP phenotype. Data
Demetris Pillas, Alexander Klein, Teresa Gasalla, Andreja Avbersek, Alexander Thompson, Jack Wright, Jennifer Mellor, Anna Scowcroft   +7 more
doaj   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

Fast Pressure-Sensitive Paint Measurement During Blast Explosion

气体物理
In blast impact research, accurately measuring the pressure-time history is critical for damage assessment, yet conventional pressure measurement techniques struggle to fully characterize the spatiotemporal pressure changes on the surfaces of test models.
Mingkai XUE, Feng GU, Long JIN, Dongpeng JIA, Shuai CHENG, Di PENG, Jun YANG   +6 more
doaj   +1 more source

Genetics of progressive supranuclear palsy in a Chinese population

Neurobiology of Disease, 2022
Background: Genetics plays an important role in progressive supranuclear palsy (PSP) and remains poorly understood. A detailed literature search identified 19 PSP-associated genes: MAPT, LRRK2, LRP10, DCTN1, GRN, NPC1, PARK, TARDBP, TBK1, BSN, GBA, STX6,
Xuewen Xiao, Qijie Yang, Yafei Wen, Bin Jiao, Xinxin Liao, Yafang Zhou, Ling Weng, Hui Liu, Tianyan Xu, Yuan Zhu, Lina Guo, Lu Zhou, Xin Wang, Xixi Liu, Xiangyun Bi, Yingzi Liu, Sizhe Zhang, Weiwei Zhang, Jinchen Li, Beisha Tang, Lu Shen   +20 more
doaj   +1 more source

From Top to Bottom: Manufacturing Process‐Context Aware Resolution of Energy Device Electrodes Through a 3D Diffusion Generative Model

Advanced Energy Materials, EarlyView.
The application of a generative diffusion model, enhanced with a training data augmentation pipeline retaining the manufacturing process context of electrode microstructures, leads to improved fidelity of the through‐plane tortuosity factor in the AI generated samples.
Victor Ramirez‐Camacho, Siwar Ben Hadj Ali, Maxence Desnoyers, Francisco Fernandez, Nassima Benammar, Alejandro A. Franco   +5 more
wiley   +1 more source