Results 61 to 70 of about 59,113 (302)

PSP PRO Photomicroscopy Contest 2018

open access: yesPhilippine Journal of Pathology, 2018
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PSP -
doaj  

Dataset Similarity Detection for Reuse Protection in Federated Data Spaces with Privacy Considerations

open access: yesApplied Sciences
Federated data spaces, established through initiatives such as IDSA and GAIA-X, enable organizations to share and monetize datasets under contractual terms.
Christos Panagiotou   +2 more
doaj   +1 more source

MicroCT reinvestigation of the only articulated fossil anostomid fish reveals synonymy of Arhinolemur Ameghino, 1898 and Megaleporinus Ramirez et al., 2017

open access: yesThe Anatomical Record, EarlyView.
Abstract Arhinolemur scalabrinii† Ameghino, 1898 was originally described as a strepsirrhine primate (Mammalia) but has been recognized as an anostomid fish since 2012. It remains the only extinct anostomid species known from complete cranial material.
Karen M. Panzeri   +8 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

A SHAP-Guided Grouped L1 Regularization Method for CRISPR-Cas9 Off-Target Predictions

open access: yesAlgorithms
CRISPR-Cas9 has emerged as a remarkably powerful gene editing tool and has advanced both research and gene therapy applications. Machine learning models have been developed to predict off-target cleavages.
Evmorfia Tentsidou, Haridimos Kondylakis
doaj   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

open access: yesBiotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney   +6 more
wiley   +1 more source

Immunostimulatory Effects of Polysaccharides from Spirulina platensis In Vivo and Vitro and Their Activation Mechanism on RAW246.7 Macrophages

open access: yesMarine Drugs, 2020
In this study, Spirulina platensis (S.p.) polysaccharide (PSP) was obtained by ultrasonic-microwave-assisted extraction (UMAE) and purified by an aqueous two-phase system (ATPS).
Xueyan Wu   +6 more
doaj   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

PSP-VDC: An Adaptation of the PSP that Incorporates Verified Design by Contract

open access: yes, 2018
The Personal Software Process (PSP) promotes the use of careful procedures during all stages of development with the aim of increasing an individual ' 's productivity and producing high quality final products.
Diego Vallespir (5407586)   +3 more
core   +1 more source

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

open access: yesBMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao   +9 more
wiley   +1 more source

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