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Microbiome: The Next Frontier in Psychedelic Renaissance
Journal of Xenobiotics, 2023 The psychedelic renaissance has reignited interest in the therapeutic potential of psychedelics for mental health and well-being. An emerging area of interest is the potential modulation of psychedelic effects by the gut microbiome—the ecosystem of ...
Robert B. Kargbo
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The Varieties of the Psychedelic Experience: A Preliminary Study of the Association Between the Reported Subjective Effects and the Binding Affinity Profiles of Substituted Phenethylamines and Tryptamines [PDF]
, 2018 Classic psychedelics are substances of paramount cultural and neuroscientific importance. A distinctive feature of psychedelic drugs is the wide range of potential subjective effects they can elicit, known to be deeply influenced by the internal state of
Federico Zamberlán +6 more
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Virtual reality and psychedelics: new perspectives and new possibilities in the treatment of alcohol use disorder [PDF]
Frontiers in PsychiatryPsychedelic-assisted therapy is a remarkably promising treatment for substance use disorders and for alcohol use disorder (AUD) in particular. Research supporting psychedelics as a safe and effective pharmacotherapy for AUD and its comorbid psychiatric ...
Scott Matthews +11 more
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Current Biology, 2022 Psychedelics are compounds that alter consciousness by acting on serotonin receptors in the brain. The term 'psychedelic', from the Greek for mind manifesting, refers to the drugs' subjective effects and was first proposed by Humphry Osmond in 1956. Other terms have been used to emphasize different aspects of the psychological experiences produced by ...
Benjamin, Kelmendi +3 more
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Case analysis of long-term negative psychological responses to psychedelics
Scientific Reports, 2023 Recent controversies have arisen regarding claims of uncritical positive regard and hype surrounding psychedelic drugs and their therapeutic potential. Criticisms have included that study designs and reporting styles bias positive over negative outcomes.
Rebecka Bremler +4 more
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Effects of psilocybin versus escitalopram on rumination and thought suppression in depression
BJPsych Open, 2022 Background Major depressive disorder is often associated with maladaptive coping strategies, including rumination and thought suppression. Aims To assess the comparative effect of the selective serotonin reuptake inhibitor escitalopram, and the ...
Tommaso Barba +8 more
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Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing
Scientific Reports, 2021 Psychedelic microdosing describes the ingestion of near-threshold perceptible doses of classic psychedelic substances. Anecdotal reports and observational studies suggest that microdosing may promote positive mood and well-being, but recent placebo ...
L. S. Kaertner +9 more
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Frontiers in Psychiatry, 2022 Survey-based studies suggest naturalistic psychedelic use provides mental health benefits similar to those observed in clinical trials. The current study sought to confirm these findings in a large group of psychedelic users and to conduct a novel ...
Charles L. Raison +4 more
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Scientific Reports, 2023 In medical trials, ‘blinding’ ensures the equal distribution of expectancy effects between treatment arms in theory; however, blinding often fails in practice.
Balázs Szigeti +3 more
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Psychedelics and Psychedelic-Assisted Psychotherapy
American Journal of Psychiatry, 2020 The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders.Searches of PubMed and PsycINFO via Ovid were conducted for articles in English, in peer-reviewed journals, reporting on "psilocybin," "lysergic acid diethylamide," "LSD," "ayahuasca," "3,4 ...
Collin M, Reiff +7 more
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