Results 91 to 100 of about 23,059 (205)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

Psychedelic-assisted therapy: Support for the REBUS hypothesis and its application to specific psychiatric illnesses

open access: yes, 2023
For centuries, psychedelic substances have been a part of human culture. Classic psychedelics such as LSD and psilocybin are characterized by their agonism of 5HT-2A receptors, and recent clinical trials have found that these substances hold great ...
Cilimburg, Wren
core  

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Psychedelic Assisted Therapy for Major Depressive Disorder: A Review

open access: yes, 2021
Psychedelic substances such as psilocybin and ketamine may represent the future of antidepressant treatment, due to their rapid and prolonged effects on mood and cognition.
Alexander De Foe   +2 more
core   +1 more source

Discovering the Self: A Grounded Theory of Women's Recovery From Gender‐Based Religious Harm

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim(s) This study defines adverse religious experiences (AREs), describes how these gendered harms affect women and develops a Classical Grounded Theory (CGT) model of women's recovery and inform trauma‐ and gender‐responsive nursing practice.
Beth K. Schwartz, Pamela H. Cone
wiley   +1 more source

Psychedelic-assisted therapy: A new way forward in mental health

open access: yes, 2019
In the following pages, I will cover many topics relating to psychedelic-assisted therapy. Initially, I explore the historical background of psychedelic use in indigenous communities around the world followed by an introduction of psychedelic-assisted ...
Wibur, Kimberly (Rosie)
core  

Registered Clinical Trials of Ayahuasca and DMT: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 94-108, July 2026.
Interest in ayahuasca and its main component, N,N‐Dimethyltryptamine (DMT), has currently moved from historical and experimental use into modern clinical development. Yet, current evidence is fragmented, and systematic mapping of trial methods and design choices remains limited.
Tijana Stojanović   +4 more
wiley   +1 more source

Psychedelic minimalism: the case against music in psychedelic therapy settings [PDF]

open access: yes
[Introduction: reframing the role of setting] In recent years, renewed attention has been given to the centrality of set and setting in psychedelic-assisted therapy.
Nader, Samir A., Samir A Nader
core   +1 more source

Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Alexander Boardman   +2 more
wiley   +1 more source

A double-edged sword : Insights from practitioners on the short and long-term negative effects of psilocybin-assisted psychological interventions

open access: yes
Background and aims: Interest in psychedelic research has grown significantly in recent years and the naturally derived substance psilocybin, in combination with therapy, has shown promising results as a treatment for a range of psychiatric conditions ...
Moa Nordin   +7 more
core   +1 more source

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