Results 21 to 30 of about 43,441 (288)

Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

Frontiers in Neuroscience, 2023
IntroductionPsilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT2A receptors, it has high binding affinity also to 5 ...
Filip Tylš, Filip Tylš, Čestmír Vejmola, Čestmír Vejmola, Vlastimil Koudelka, Václava Piorecká, Václava Piorecká, Lukáš Kadeřábek, Marcel Bochin, Marcel Bochin, Tomáš Novák, Tomáš Novák, Martin Kuchař, Martin Kuchař, Zdeňka Bendová, Martin Brunovský, Martin Brunovský, Jiří Horáček, Jiří Horáček, Tomáš Pálení ček, Tomáš Pálení ček   +20 more
doaj   +1 more source

Inhibition of alpha oscillations through serotonin-2A receptor activation underlies the visual effects of ayahuasca in humans [PDF]

, 2016
Ayahuasca is an Amazonian psychotropic plant tea typically obtained from two plants, Banisteriopsis caapi and Psychotria viridis. It contains the psychedelic 5-HT2A and sigma-1 agonist N,N-dimethyltryptamine (DMT) plus ß-carboline alkaloids with ...
Alonso, Joan Francesc, Antonijoan Arbós, Rosa Ma (Rosa María), Barker, Steven, Feilding, Amanda, Friedlander, Pablo, Maqueda, Ana Elda, Mañanas, Miquel Àngel, Rabella, Mireia, Riba, Jordi, Rodríguez-Pujadas, Aina, Romero, Sergio, Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia, Valle, Marta   +12 more
core   +3 more sources

Recreational use, analysis and toxicity of tryptamines [PDF]

, 2015
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio, Pantano, Flaminia, Romolo, Francesco Saverio, Tittarelli, Roberta   +3 more
core   +1 more source

Psychedelic Cognition—The Unreached Frontier of Psychedelic Science

Frontiers in Neuroscience, 2022
Psychedelic compounds hold the promise of changing the face of neuroscience and psychiatry as we know it. There have been numerous proposals to use them to treat a range of neuropsychiatric conditions such as depression, anxiety, addiction and PTSD; and trials to date have delivered positive results in favor of the novel therapeutics.
openaire   +5 more sources

Psychedelics and Personality [PDF]

ACS Chemical Neuroscience, 2018
In the past decade, an increasing number of clinical trials are reporting evidence that psychedelics or serotonergic hallucinogens (such as lysergic acid diethylamide, psilocybin, and ayahuasca/dimethyltryptamine) could be effective in the treatment of mood, anxiety, and substance use disorders.
Marc, Aixalà, Rafael G, Dos Santos, Jaime E C, Hallak, José Carlos, Bouso   +3 more
openaire   +2 more sources

What Conceptual Metaphors Appear in Texts on Psychedelics and Medicine? Corpus-Based Cognitive Study

Respectus Philologicus, 2022
This paper aims to present conceptual metaphors employed to discuss psychedelics in texts published online by organizations popularizing knowledge about psychedelic substances. The foundation of this investigation comprises Cognitive Grammar, Conceptual
Milena Bryła
doaj   +1 more source

Herbal highs: review on psychoactive effects and neuropharmacology [PDF]

, 2017
Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S, Orsolini, L, Pichini, S., Rotolo, Mc, Schifano, F, Tittarelli, R   +5 more
core   +1 more source

Interest in receiving psychedelic-assisted therapy among marginalized women: Implications and findings from a community-based study in Canada

Drug and Alcohol Dependence Reports, 2022
Background: Psychedelic-assisted therapies are receiving mounting attention for their therapeutic potential. However, little is known about interest among women who experience elevated risk of mental health and substance use disorders.
Elena Argento, Shira Goldenberg, Kathleen Deering, Jennifer Lavalley, Melissa Braschel, Brittany Bingham, Kate Shannon   +6 more
doaj   +1 more source

Psychedelic minimalism: the case against music in psychedelic therapy settings. [PDF]

Front Psychiatry
Nader SA.
europepmc   +3 more sources

Relational Processes in Ayahuasca Groups of Palestinians and Israelis

Frontiers in Pharmacology, 2021
Psychedelics are used in many group contexts. However, most phenomenological research on psychedelics is focused on personal experiences. This paper presents a phenomenological investigation centered on intersubjective and intercultural relational ...
Leor Roseman, Yiftach Ron, Yiftach Ron, Antwan Saca, Natalie Ginsberg, Lisa Luan, Nadeem Karkabi, Rick Doblin, Robin Carhart-Harris   +8 more
doaj   +1 more source