Results 111 to 120 of about 10,405 (213)

Neural signaling mechanisms in depression: bridging classical monoamine hypotheses, animal models, and emerging antidepressant strategies

open access: yesFrontiers in Cell and Developmental Biology
Major depressive disorder is a highly prevalent psychiatric condition that can affect individuals across the lifespan, yet its pathophysiology remains incompletely understood. Classical hypotheses, informed by preclinical and clinical studies, emphasized
Mizuki Yamamoto   +2 more
doaj   +1 more source

A STUDY ON THE REGULATORY STATUS OF PSYCHEDELICS IN KOREA AND THEIR ADMISSIBILITY AS THERAPEUTIC AGENTS

open access: yesInternational Journal of Neuropsychopharmacology
Abstract Background Korea has strict controls on narcotics. Nonetheless, as the impact of research on the therapeutic use of marijuana, psychedelics, etc. discussions on their medical use are beginning in Korea. Aims & Objects The
Sohn, *Inki, Jeong, Jong-Hyun
openaire   +1 more source

Serotonin 5-HT2A receptor expression is chronically decreased in the anterior cerebral cortex of male rats following repetitive low-level blast exposure

open access: yesFrontiers in Neurology
IntroductionMany Veterans who experienced blast-related traumatic brain injuries (TBIs) in Iraq and Afghanistan currently suffer from chronic cognitive and mental health problems that include depression and post-traumatic stress disorder (PTSD).
Rita De Gasperi   +21 more
doaj   +1 more source

Sedition, December 1, 1971 [PDF]

open access: yes, 1971
Volume 1, Issue 4https://scholarworks.sjsu.edu/sedition/1006/thumbnail ...
Graphic Offensive
core   +1 more source

Healing a Broken System: Veterans and the War on Drugs [PDF]

open access: yes, 2012
This report examines the plight of returning veterans who struggle with incarceration and psychological wounds of war such as addiction and post-traumatic stress disorder -- and suggests reforms that could improve the health and preserve the freedom of ...

core  

The potential of non-psychedelic 5-HT2A agents in the treatment of substance use disorders: a narrative review of the clinical literature

open access: yesExpert Opinion on Pharmacotherapy
Substance use disorders (SUDs) are a public health issue, with only some having FDA-approved indicated treatments and these having high attrition. Consequently, there has been interest in novel interventions (e.g. psychedelics that target 5-HT2A receptors) with some promising results.
Alejandra Pulido-Saavedra   +7 more
openaire   +2 more sources

Short-term safety and tolerability profile of 5-methoxy-N,N-dimethyltryptamine in human subjects: a systematic review of clinical trials

open access: yesFrontiers in Psychiatry
IntroductionPsychedelic agents have regained the attention of pharmaceutical companies as promising treatments for depressive episodes. 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT), an atypical psychedelic, is emerging as a potentially effective, novel ...
Aleksander Kwaśny   +2 more
doaj   +1 more source

Psychedelics in developmental stuttering to modulate brain functioning: a new therapeutic perspective?

open access: yesFrontiers in Human Neuroscience
Developmental stuttering (DS) is a neurodevelopmental speech-motor disorder characterized by symptoms such as blocks, repetitions, and prolongations. Persistent DS often has a significant negative impact on quality of life, and interventions for it have ...
Giuseppe Pasculli   +14 more
doaj   +1 more source

“” A Qualitative Analysis of Patient Perspectives on Psychedelic-Assisted Therapy for Cancer-Related Psychosocial Symptoms

open access: yesIntegrative Cancer Therapies
People living with cancer (PLWC) often face profound existential distress that is insufficiently addressed by conventional psychosocial supports. This qualitative study explored PLWC’s attitudes, beliefs, and experiences regarding psychedelic-assisted ...
Haley D.M. Schuman BSc   +5 more
doaj   +1 more source

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