Results 61 to 70 of about 19,917 (245)
ELECTROPHORESIS, EarlyView.This review provides a comprehensive summary of monoamine neurotransmitter analysis by capillary electrophoresis with amperometric detection. Fundamental principles of amperometric detection, electrode positioning strategies, and approaches to high‐voltage decoupling are described, followed by a critical comparison of electrode materials, selection of ...
Petr Kubáň +3 more
wiley +1 more source
Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges
Epilepsia, EarlyView.Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod +26 more
wiley +1 more source
Age at first episode modulates diagnosis-related structural brain abnormalities in psychosis [PDF]
, 2015 Brain volume and thickness abnormalities have been reported in first-episode psychosis (FEP). However, it is unclear if and how they are modulated by brain developmental stage (and, therefore, by age at FEP as a proxy).
Arango, Celso +14 more
core +1 more source
Epilepsia, EarlyView.Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte +15 more
wiley +1 more source
Comorbidity of mental disorders and substance use: A brief guide for the primary care clinician [PDF]
, 2008 Comorbidity or the co-occurrence of mental disorders and substance use disorders is common. However there are significant problems with the management of people with comorbidity and a dearth of evidence about best practice.
Holmwood, Chris
core
Epilepsia Open, EarlyView.Abstract Objective To clinically validate the contribution of a custom‐built EEG wearable device (waEEG) compared to a full 10–20 electrode array ambulatory EEG (aEEG) for screening epilepsy cases in patients with suspected temporal lobe epilepsy (TLE) but negative routine EEGs. Methods Patients (aged 16–91 years) with clinically suspected TLE who were
Daniel Filipe Borges +4 more
wiley +1 more source
Aberrant salience in cannabis-induced psychosis: a comparative study
Frontiers in PsychiatryBackgroundNatural Cannabis (NC) and Synthetic Cannabinoids (SCs) use can increase the risk and exacerbate the course of psychotic disorders. These could be influenced by the Aberrant Salience (AS) construct.
Valerio Ricci +13 more
doaj +1 more source
Prevalence and risk factors for HIV, hepatitis B, and hepatitis C in people with severe mental illness: a total population study of Sweden [PDF]
, 2017 BACKGROUND: Severe mental illness is associated with increased morbidity and mortality. The elevated risk of blood-borne viruses (BBVs) in people with severe mental illness is of concern, but the full extent of this problem is unclear.
Bauer-Staeb, C +5 more
core +1 more source
European Eating Disorders Review, EarlyView.ABSTRACT Introduction Anorexia nervosa (AN) and autism are distinct conditions, yet individuals with AN often exhibit elevated autistic traits. These traits are linked to complex clinical presentations, but their impact on AN remains unclear. This longitudinal study investigates associations between autistic traits, AN symptoms, and weight recovery in ...
Janneke S. van der Linden +5 more
wiley +1 more source
TULP4, a novel E3 ligase gene, participates in neuronal migration as a candidate in schizophrenia
CNS Neuroscience &Therapeutics, EarlyView., 2023 Mutations identified from four SCZ pedigrees resulted in decreased TULP4 expression. Tulp4 knockdown caused delayed neuron migration in embryonic mice, and impaired cognition and prepulse inhibition in adult mice. These phenotypes may be related to TULP4 through its involvement in the formation of a novel E3 ubiquitin ligases.
Yan Bi +19 more
wiley +1 more source