Analytical strategy to investigate 3,4-methylenedioxypyrovalerone (MDPV) metabolites in consumers’ urine by high-resolution mass spectrometry [PDF]
The potential of high-resolution mass spectrometry (HRMS) for the investigation of human in vivo metabolism of 3,4-methylenedioxypyrovalerone (MDPV) using urine collected from a consumer (this is, in non-controlled experiments) has been investigated.
Haro, Gonzalo +5 more
core +2 more sources
ABSTRACT Background There is ample evidence on the efficacy of different therapeutic approaches in treating eating disorders. Yet, studies on the effectiveness of inpatient/day‐hospital treatment of eating disorders are rare. Method Data were retrieved from a naturalistic multi‐center effectiveness study of inpatient and day‐hospital treatment in ...
Magdalena Pape +42 more
wiley +1 more source
Mental health: Future challenges [Mental Capital and Wellbeing: Making the most of ourselves in the 21st century] [PDF]
The aim of the Foresight Project on Mental Capital and Wellbeing (www.foresight.gov.uk) is to advise the Government on how to achieve the best possible mental development and mental wellbeing for everyone in the UK in the future. The starting point
Bebbington, P +7 more
core
Postictal psychosis: presymptomatic risk factors and the need for further investigation of genetics and pharmacotherapy [PDF]
Background Postictal psychosis (PIP), an episode of psychosis occurring after a cluster of seizures, is common and may be associated with profound morbidity, including chronic psychosis.
Eric M Morrow +3 more
core +1 more source
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi +13 more
wiley +1 more source
The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]
Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core +1 more source
Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley +1 more source
Is cannabis use a contributory cause of psychosis? [PDF]
Objective: To assess whether cannabis use in adolescence and young adulthood is a contributory cause of schizophreniform psychosis in that it may precipitate psychosis in vulnerable individuals. Method: We reviewed longitudinal studies of adolescents and
Anthony JC +12 more
core +1 more source
Abstract Background We conducted a systematic review and meta‐analysis to examine the effects of mindfulness‐based interventions (MBIs) on emotion regulation (ER) and emotion dysregulation (ED) in people with any mental health condition. Methods Following a pre‐registered protocol (PROSPERO CRD42024618605), we searched multiple databases (Web of ...
Thomas Easdale‐Cheele +4 more
wiley +1 more source
Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder : a systematic review [PDF]
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with high heritability rates. The contribution of genetic factors to the etiology of these disorders is increasingly being recognized as the action of multiple risk ...
Frydecka, Dorota +6 more
core

