Results 71 to 80 of about 19,768 (236)
Rapid tranquillisation for agitated patients in emergency psychiatric rooms: a randomised trial of midazolam versus haloperidol plus promethazine [PDF]
OBJECTIVE: To compare two widely used drug treatments for people with aggression or agitation due to mental illness. DESIGN: Pragmatic, randomised clinical trial. SETTING: Three psychiatric emergency rooms in Rio de Janeiro, Brazil. SUBJECTS:
Abreu, A.M. +13 more
core +1 more source
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri +20 more
wiley +1 more source
Mismatch negativity generation in the human 5HT agonist and NMDA antagonist model of psychosis [PDF]
RATIONALE: Many studies have reported deficits of mismatch negativity (MMN) in schizophrenic patients. Pharmacological challenges with hallucinogens in healthy humans are used as models for psychotic states.
Karsten Heekeren +46 more
core +2 more sources
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
Age at first episode modulates diagnosis-related structural brain abnormalities in psychosis [PDF]
Brain volume and thickness abnormalities have been reported in first-episode psychosis (FEP). However, it is unclear if and how they are modulated by brain developmental stage (and, therefore, by age at FEP as a proxy).
Arango, Celso +14 more
core +1 more source
Serial maternal filicide as evidence of Munchausen syndrome by proxy
Abstract Munchausen Syndrome by Proxy (MSBP), or Fabricated or Induced Illness (FII), is a form of physical and emotional child abuse and maltreatment that remains frequently under‐detected due to a significant lack of clinical awareness. This case report aims to highlight the challenges of diagnosing MSBP, its impact on victims, and the ethical ...
Ahlem Mtiraoui +4 more
wiley +1 more source
Abstract Background Posttraumatic stress disorder (PTSD) is associated with autonomic dysfunction as indicated by deficits in the sympathetic and parasympathetic nervous systems. These abnormalities are expressed as elevated heart rate and reduced heart rate variability (HRV), respectively.
Camila Cosmo +4 more
wiley +1 more source
Prevalence and risk factors for HIV, hepatitis B, and hepatitis C in people with severe mental illness: a total population study of Sweden [PDF]
BACKGROUND: Severe mental illness is associated with increased morbidity and mortality. The elevated risk of blood-borne viruses (BBVs) in people with severe mental illness is of concern, but the full extent of this problem is unclear.
Bauer-Staeb, C +5 more
core +1 more source
ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian +3 more
wiley +1 more source
The Swedish National Quality Register for Repetitive Transcranial Magnetic Stimulation
ABSTRACT Objective Repetitive transcranial magnetic stimulation (rTMS) has been demonstrated to be an effective and well tolerated treatment for depression, and it is being investigated also for other indications. This study presents the Swedish National Quality Register for rTMS (Q‐rTMS).
S. Melker Hagsäter +6 more
wiley +1 more source

