Results 91 to 100 of about 396,678 (362)

Rüdin's Unpublished Family Study From the Early 1920s: “On the Inheritance of Manic‐Depressive Insanity”

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Ernst Rüdin, an important and controversial figure in the history of psychiatric genetics, published only one major empirical study on siblings of dementia praecox (DP) probands in 1916. He conducted a parallel study of siblings of probands with manic‐depressive insanity (MDI), but the resulting monograph, written in the early 1920s, was left ...
Kenneth S. Kendler, Astrid Klee
wiley   +1 more source

Schizophrenia Genetics Modulates Clinical Depressive Features

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Schizophrenia (SCZ) genetic liability, quantified by polygenic scores (PGS), may influence clinical phenotypes in major depressive disorder (MDD). We investigated the effect of the SCZ‐PGS derived from the latest SCZ genome‐wide association study (GWAS) on MDD symptom severity, comorbidities, and treatment outcomes.
Alessandro Serretti   +13 more
wiley   +1 more source

Reasons for disengagement in first-episode psychosis – perspectives from service users and their caregivers

open access: yesBMC Psychiatry
Background The efforts of early psychosis intervention programmes can be impeded by difficulties in maintaining the engagement of service users. As disengagement is often an autonomous decision made by service users, the main aim of this study was to ...
Yi Chian Chua   +4 more
doaj   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra   +5 more
wiley   +1 more source

Towards a scalable approach to assess speech organization across the psychosis-spectrum -online assessment in conjunction with automated transcription and extraction of speech measures

open access: yesTranslational Psychiatry
Automatically extracted measures of speech constitute a promising marker of psychosis as disorganized speech is associated with psychotic symptoms and predictive of psychosis-onset.
Julianna Olah   +9 more
doaj   +1 more source

Understanding Youth Assaults of Police Officers in Australia: A Power Threat Meaning Framework Analysis

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT This study explores youth violence towards police officers in Australia through the Power Threat Meaning Framework (PTMF) to better understand the underlying factors contributing to such violence; focusing on power dynamics, childhood adversity, and trauma.
Dimitra Lattas   +4 more
wiley   +1 more source

Traumatic Experiences, Psychological Distress and Suicide‐Related Behaviors in Autistic Adults

open access: yesAutism Research, EarlyView.
ABSTRACT Autistic adults have increased risks of trauma, suicide, and poor mental health compared to non‐autistic adults, with 1 in 4 autistic adults attempting suicide. We administered an anonymized, self‐report survey to 424 autistic and 345 non‐autistic adults through a convenience sampling framework.
T. A. Chikaura   +9 more
wiley   +1 more source

Psychiatric Emergency Visits of Autistic Adults With or Without Documented Borderline Personality Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT Autism and borderline personality disorder (BPD) are each associated with increased psychiatric emergency department (PsyED) use, yet the service impact of coexisting autism–BPD remains unclear. We conducted a retrospective chart review of 1027 PsyED visits by 345 autistic adults (2018–2020) at an urban Canadian psychiatric hospital to compare
Ching‐Hua Julie Lee   +15 more
wiley   +1 more source

Feasibility Study of a Novel App‐Based Anxiety Intervention for Autistic People

open access: yesAutism Research, EarlyView.
ABSTRACT At least 50% of autistic people experience clinically relevant anxiety symptoms. However, reasons for elevated rates of anxiety in autism remain poorly understood and there is a high unmet need for novel and adapted therapies for anxiety that are accessible to autistic people.
Bethany Oakley   +18 more
wiley   +1 more source

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