Results 11 to 20 of about 396,678 (362)

Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders

open access: yesScientific Reports, 2023
Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in mental disorders.
Monica Aas   +11 more
doaj   +1 more source

Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]

open access: yes, 2016
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R   +4 more
core   +2 more sources

Study protocol design and evaluation of a hospital-based multi-professional educational intervention: Person-Centred Psychosis Care (PCPC)

open access: yesBMC Psychiatry, 2018
Background While patient involvement in mental health care is repeatedly stressed in policy documents, there are actually few studies that evaluate person-centred care interventions within psychiatric services.
Anneli Goulding   +4 more
doaj   +1 more source

Investigating Trajectories of Social Recovery in Individuals with First Episode Psychosis:A Latent Class Growth Analysis [PDF]

open access: yes, 2015
Background Social disability is a hallmark of severe mental illness yet individual differences and factors predicting outcome are largely unknown. Aim To explore trajectories and predictors of social recovery following a first episode of psychosis (FEP).
Amos, Tim   +12 more
core   +2 more sources

A History of Trauma is Associated with Aggression, Depression, Non-Suicidal Self-Injury Behavior, and Suicide Ideation in First-Episode Psychosis. [PDF]

open access: yes, 2019
The association between trauma and psychosis outcomes is well-established, and yet the impact of trauma on comorbid clinical symptoms-such as aggression, non-suicidal self-injury behavior (NSSIB), suicide ideation, and suicide behavior-for those with ...
Botello, Renata M   +6 more
core   +1 more source

Analysis of risk factor domains in psychosis patient health records

open access: yesJournal of Biomedical Semantics, 2019
Background Readmission after discharge from a hospital is disruptive and costly, regardless of the reason. However, it can be particularly problematic for psychiatric patients, so predicting which patients may be readmitted is critically important but ...
Eben Holderness   +6 more
doaj   +1 more source

Public health primary prevention implemented by clinical high-risk services for psychosis

open access: yesTranslational Psychiatry, 2022
Clinical High Risk for Psychosis (CHR-P) services have been primarily developed to support young people with attenuated symptoms (indicated prevention).
Andrés Estradé   +5 more
doaj   +1 more source

Treatment dilemmas in a young man presenting with narcolepsy and psychotic symptoms. [PDF]

open access: yes, 2011
Psychotic features can be present in both narcolepsy and psychosis, which can result in challenges in diagnosis and management. The prevalence of both conditions is low and the reports in young people are scarce. Our report illustrates the relevance of a
Davies, S, Fernandez, V, Walters, N
core   +2 more sources

Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report

open access: yesBMC Pharmacology and Toxicology, 2020
Background Acute pancreatitis is a rare but recognised complication of clozapine leading to termination of treatment. Case presentation We present the case of a 39-year-old man with treatment-resistant schizoaffective disorder and a history of recurrent ...
Victoria Rodriguez   +6 more
doaj   +1 more source

Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia

open access: yesnpj Schizophrenia, 2022
The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N ...
Fanni Krajner   +15 more
doaj   +1 more source

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