Results 11 to 20 of about 191,827 (269)

Analysis of risk factor domains in psychosis patient health records

Journal of Biomedical Semantics, 2019
Background Readmission after discharge from a hospital is disruptive and costly, regardless of the reason. However, it can be particularly problematic for psychiatric patients, so predicting which patients may be readmitted is critically important but ...
Eben Holderness, Nicholas Miller, Philip Cawkwell, Kirsten Bolton, Marie Meteer, James Pustejovsky, Mei-Hua Hall   +6 more
doaj   +1 more source

Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders

Scientific Reports, 2023
Exposure to early life trauma increases the risk of psychopathology later in life. Here we investigated if ANK3 mRNA levels influence the relationship between childhood trauma experiences and clinical characteristics in mental disorders.
Monica Aas, Ole A. Andreassen, Johannes Gjerstad, Linn Rødevand, Gabriela Hjell, Ingrid Torp Johansen, Synve Hoffart Lunding, Monica B. E. G. Ormerod, Trine V. Lagerverg, Nils Eiel Steen, Srdjan Djurovic, Ibrahim Akkouh   +11 more
doaj   +1 more source

Public health primary prevention implemented by clinical high-risk services for psychosis

Translational Psychiatry, 2022
Clinical High Risk for Psychosis (CHR-P) services have been primarily developed to support young people with attenuated symptoms (indicated prevention).
Andrés Estradé, Gonzalo Salazar de Pablo, Alice Zanotti, Scott Wood, Helen L. Fisher, Paolo Fusar-Poli   +5 more
doaj   +1 more source

Reading emotions from body movement: a generalized impairment in schizophrenia

Frontiers in Psychology, 2016
Body language reading is a social cognitive process with importance for successful maneuvering of social situations. In this study, we investigated body language reading as assessed with human point-light displays in participants with a diagnosis of ...
Anja eVaskinn, Anja eVaskinn, Kjetil eSundet, Kjetil eSundet, Tiril eØstefjells, Tiril eØstefjells, Katharina eNymo, Katharina eNymo, Ingrid eMelle, Ingrid eMelle, Torill eUeland, Torill eUeland   +11 more
doaj   +1 more source

Successful clozapine rechallenge following recurrent clozapine-associated pancreatitis: a case report

BMC Pharmacology and Toxicology, 2020
Background Acute pancreatitis is a rare but recognised complication of clozapine leading to termination of treatment. Case presentation We present the case of a 39-year-old man with treatment-resistant schizoaffective disorder and a history of recurrent ...
Victoria Rodriguez, Kieran Hanley, Ana Julia Arias, Diego Quattrone, Joseph Kuforiji, Eromona Whiskey, Sukhi S. Shergill   +6 more
doaj   +1 more source

Does negative-self-schema link the relationship between childhood trauma and psychotic symptoms in a community sample of Indonesians?

Konselor, 2019
Childhood trauma is a risk factor that influences the development of psychotic symptoms. Negative-self-schema is a psychological response to trauma, which is known to have impact on psychotic symptoms’ level, thus postulated as the underlying mechanism ...
Shierlen Octavia, Sali Rahadi Asih, Edo Sebastian Jaya   +2 more
doaj   +1 more source

Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia

npj Schizophrenia, 2022
The neurobiological effects of clozapine are under characterised. We examined the effects clozapine treatment on subcortical volume and cortical thickness and investigated whether macrostructural changes were linked to alterations in glutamate or N ...
Fanni Krajner, Laila Hadaya, Grant McQueen, Kyra-Verena Sendt, Amy Gillespie, Alessia Avila, John Lally, Emily P. Hedges, Kelly Diederen, Oliver D. Howes, Gareth J. Barker, David J. Lythgoe, Matthew J. Kempton, Philip McGuire, James H. MacCabe, Alice Egerton   +15 more
doaj   +1 more source

The role of perceived discrimination in mediating the relationship between minority status and psychotic symptoms in a community sample

Konselor, 2019
Minority groups have been found to be at higher risk of developing psychotic symptoms, but the underlying mechanism is yet to be established. This study aims to determine the mechanism that underlies the relationship between minority status and psychotic
Eko Hermanto, Sali Rahadi Asih, Edo Sebastian Jaya   +2 more
doaj   +1 more source

N-Methyl-D-Aspartate Receptor availability in First-Episode Psychosis: a multi-modal PET-MR brain imaging study

European Psychiatry, 2022
Introduction N-Methyl-D-Aspartate Receptor (NMDAR) hypofunction is hypothesised to underlie psychosis but this has not been tested early in illness. Objectives Our aim was to determine if NMDAR availability was lower in patients with first episode ...
K. Beck, A. Arumuham, S. Brugger, R. Mccutcheon, M. Veronese, S. Kaar, T. Pillinger, J. Stone, O. Howes   +8 more
doaj   +1 more source

Glutamate connectivity associations converge upon the salience network in schizophrenia and healthy controls

Translational Psychiatry, 2021
Alterations in cortical inter-areal functional connectivity, and aberrant glutamatergic signalling are implicated in the pathophysiology of schizophrenia but the relationship between the two is unclear.
Robert A. McCutcheon, Toby Pillinger, Maria Rogdaki, Juan Bustillo, Oliver D. Howes   +4 more
doaj   +1 more source