Results 41 to 50 of about 250,129 (223)

Successful switching from risperidone to cariprazine in a schizophrenic patient with pronounced functional deficit. Case report

open access: yesFrontiers in Psychiatry, 2023
A 22-year-old male was admitted to an in-patient psychiatric unit for treatment, after a period of 2 years of increasing psychotic symptoms corresponding to a very severe case of schizophrenia across the entire scale of symptom disorder domains along ...
Johan Sahlsten Schölin   +2 more
doaj   +1 more source

Power Spectral Density-Based Resting-State EEG Classification of First-Episode Psychosis [PDF]

open access: yesarXiv, 2022
Historically, the analysis of stimulus-dependent time-frequency patterns has been the cornerstone of most electroencephalography (EEG) studies. The abnormal oscillations in high-frequency waves associated with psychotic disorders during sensory and cognitive tasks have been studied many times. However, any significant dissimilarity in the resting-state
arxiv  

Cortical patterning of abnormal morphometric similarity in psychosis is associated with brain expression of schizophrenia-related genes

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Despite significant research, the biological mechanisms underlying schizophrenia are still unclear. We shed light on structural brain differences in psychosis using an approach called morphometric similarity mapping, which quantifies the ...
S. Morgan   +16 more
semanticscholar   +1 more source

Delving into the world of webCHAT – an e-mental health support service for distressed youths in Singapore

open access: yesDigital Health
Background Young people face high rates of mental health issues, yet many do not seek professional help. In 2017, CHAT launched webCHAT – a free, anonymous, one-on-one synchronous web-based text service managed by case managers (CMs) to support young ...
Yi Ping Lee   +5 more
doaj   +1 more source

The Implementation and Review of Cognitive Remediation Training for First Episode Psychosis in Singapore

open access: yesFrontiers in Psychiatry, 2021
Objective: Early intervention in patients with first episode psychosis (FEP) can improve cognitive abilities, with both short- and long-term benefits. In this paper, we describe the implementation and review of cognitive remediation training (CRT) in an ...
Nigel Ian Ming Chong   +3 more
doaj   +1 more source

Network controllability in transmodal cortex predicts psychosis spectrum symptoms [PDF]

open access: yesarXiv, 2020
The psychosis spectrum is associated with structural dysconnectivity concentrated in transmodal association cortex. However, understanding of this pathophysiology has been limited by an exclusive focus on the direct connections to a region. Using Network Control Theory, we measured variation in both direct and indirect structural connections to a ...
arxiv  

Delayed closed-loop neurostimulation for the treatment of pathological brain rhythms in mental disorders [PDF]

open access: yesarXiv, 2023
Mental disorders (MD) are among the top most demanding challenges in world-wide health. According to the World Health Organization, the burden of MDs continues to grow with significant impact on health and major social and human rights. A large number of MDs exhibit pathological rhythms, which serve as the disorders characteristic biomarkers.
arxiv  

An Individualized Risk Calculator for Research in Prodromal Psychosis.

open access: yesAmerican Journal of Psychiatry, 2016
OBJECTIVE Approximately 20%-35% of individuals 12-35 years old who meet criteria for a prodromal risk syndrome convert to psychosis within 2 years. However, this estimate ignores the fact that clinical high-risk cases vary considerably in risk.
Tyrone D. Cannon   +15 more
semanticscholar   +1 more source

Sex Selection Bias in Schizophrenia Antipsychotic Trials—An Update Systematic Review

open access: yesWomen, 2021
The lack of female participation in antipsychotic trials for schizophrenia poses an important issue regarding its applicability, with direct and real-life repercussions to clinical practice. Here, our aim is to systematically review the sampling sex bias
Lais Fonseca   +5 more
doaj   +1 more source

Improving outcomes of first‐episode psychosis: an overview

open access: yesWorld Psychiatry, 2017
Outcomes of psychotic disorders are associated with high personal, familiar, societal and clinical burden. There is thus an urgent clinical and societal need for improving those outcomes.
P. Fusar-Poli, P. McGorry, J. Kane
semanticscholar   +1 more source

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