Results 51 to 60 of about 250,129 (223)
The psychosis high-risk state: a comprehensive state-of-the-art review.
JAMA psychiatry, 2013 CONTEXT During the past 2 decades, a major transition in the clinical characterization of psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for psychosis has evolved to capture the prepsychotic phase, describing people ...
P. Fusar-Poli +22 more
semanticscholar +1 more source
Ten year neurocognitive trajectories in first-episode psychosis
Frontiers in Human Neuroscience, 2013 Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship to clinically significant ...
Helene Eidsmo Barder +27 more
doaj +1 more source
Cannabidiol as a potential treatment for psychosis
Therapeutic Advances in Psychopharmacology, 2019 Psychotic disorders such as schizophrenia are heterogeneous and often debilitating conditions that contribute substantially to the global burden of disease. The introduction of dopamine D2 receptor antagonists in the 1950s revolutionised the treatment of
C. Davies, S. Bhattacharyya
semanticscholar +1 more source
A Network Approach to Psychosis: Pathways Between Childhood Trauma and Psychotic Symptoms
Schizophrenia bulletin, 2017 Childhood trauma (CT) has been identified as a potential risk factor for the onset of psychotic disorders. However, to date, there is limited consensus with respect to which symptoms may ensue after exposure to trauma in early life, and whether specific ...
A. Isvoranu +5 more
semanticscholar +1 more source
BJPsych Open, 2017 A case is presented of a 30-year-old female with treatment-resistant schizoaffective disorder who was referred to a tertiary-level specialist psychosis service.
Jessica Foster +3 more
doaj +1 more source
Psychosis as a transdiagnostic and extended phenotype in the general population
World Psychiatry, 2016 A large body of research indicates that weak expressions of positive psychotic symptoms (“psychotic experiences”) can be measured in the general population, and likely represent the behavioural manifestation of distributed multifactorial (genetic and non‐
J. van os, U. Reininghaus
semanticscholar +1 more source
Subtyping brain diseases from imaging data [PDF]
arXiv, 2022 The imaging community has increasingly adopted machine learning (ML) methods to provide individualized imaging signatures related to disease diagnosis, prognosis, and response to treatment. Clinical neuroscience and cancer imaging have been two areas in which ML has offered particular promise.
arxiv
Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers.
American Journal of Psychiatry, 2016 OBJECTIVE Clinical phenomenology remains the primary means for classifying psychoses despite considerable evidence that this method incompletely captures biologically meaningful differentiations.
B. Clementz +7 more
semanticscholar +1 more source
International Journal of Bipolar Disorders, 2017 Background Individuals with bipolar disorder present with moderate impairments in social cognition during the euthymic state. The impairment extends to theory of mind and to the perception of emotion in faces and voices, but it is unclear if emotion ...
Anja Vaskinn +6 more
doaj +1 more source
Pattern classification of brain activation during emotional processing in subclinical depression: psychosis proneness as potential confounding factor [PDF]
PeerJ, 2013 We used Support Vector Machine (SVM) to perform multivariate pattern classification based on brain activation during emotional processing in healthy participants with subclinical depressive symptoms.
Gemma Modinos +5 more
doaj +2 more sources