Results 111 to 120 of about 207,857 (302)

Copula‐based joint modelling of emergency department visits with time‐varying dependence

Canadian Journal of Statistics, EarlyView.
Abstract Jointly modelling multiple correlated count time series is essential in health services research, where outcomes like emergency visits for mental health and substance use often evolve together. Ignoring these dependencies can obscure meaningful trends and limit the effectiveness of policy evaluation.
Guanjie Lyu, Cindy Feng, Lihui Liu
wiley   +1 more source

Psychotic-like experiences in the general population: characterizing a high-risk group for psychosis.

, 2011
Recent research shows that psychotic symptoms, or psychotic-like experiences (PLEs), are reported not only by psychosis patients but also by healthy members of the general population.
Mary Cannon (7895894), Ian Kelleher (7899044), Mary Cannon (480296), Ian Kelleher (480289)   +3 more
core   +1 more source

Comparison of beta-endorphin and CGRP levels before and after treatment for severe schizophrenia

Neuropsychiatric Disease and Treatment, 2016
Małgorzata Urban-Kowalczyk,1 Janusz Śmigielski,2 Dominik Strzelecki1 1Department of Affective and Psychotic Disorders, 2Department of Geriatrics, Healthy Aging Research Centre (HARC), Medical University of Lodz, Lodz, Poland ...
Urban-Kowalczyk M, Smigielski J, Strzelecki D   +2 more
doaj  

A case report of adolescent lactation due to the drug blonanserin

BMC Psychiatry
Background Second-generation antipsychotic drugs are increasingly used to treat depressive disorders with psychotic symptoms. In addition to effectively managing psychotic symptoms, second-generation antipsychotics can also result in adverse drug ...
Peiyuan Tang, Chongze Wang, Wu Hong, Zhenghui Yi, Qinyu Lv   +4 more
doaj   +1 more source

Dysfunctional GABAergic inhibition in the prefrontal cortex leading to "psychotic" hyperactivation-0

, 2011
, which are connected reciprocally and have also self-innervations. All populations of neurons are under dopaminergic modulation via D1 receptors. The transient input to the pyramidal neurons triggers the dynamics of the circuit.Copyright information ...
Shoji Tanaka (92049)
core   +1 more source

Irregular visits in longitudinal studies: Comparing inverse intensity of visit weighting and imputation in a causal analysis of antidepressant therapeutic treatment

Canadian Journal of Statistics, EarlyView.
Abstract Irregular observation times are common in longitudinal observational studies and can affect causal inferences. We use data from electronic health records of Kaiser Permanente Washington patients in the United States who initiated an antidepressant medication between 2008 and 2018, with a confirming diagnosis of depression. We are interested in
Janie Coulombe, Erica E. M. Moodie, Susan M. Shortreed   +2 more
wiley   +1 more source

Commentary: Vitamin D Deficiency Associated with Cognitive Functioning in Psychotic Disorders

Frontiers in Public Health, 2017
Leo Sher
doaj   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source

Cannabis and psychosis : the Maltese contribution [PDF]

, 2010
Three different Maltese scientists have contributed to research on the link between cannabis and psychosis. The object of this article is to review and chronicle the work that has been done by these three colleagues in this field.
Agius, Mark, Zammit, Stanley, Grech, Anton   +2 more
core  

Unintended Pregnancies and Breastfeeding Studies during Central Nervous System Drug Development: How Are they Handled, Is There Room for Improvement?

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant and breastfeeding individuals are routinely excluded from clinical drug development, creating persistent evidence gaps in pharmacology, safety, and dosing. Despite mandatory contraception and pregnancy testing, unintended pregnancies occur, particularly during the development of central nervous system (CNS) medicines used by women of ...
Sam Schoenmakers, Charlotte Bakker, Alexandra Ganev, Florence Butlen‐Ducuing, Corinne S. de Vries   +4 more
wiley   +1 more source