Results 111 to 120 of about 3,597,475 (336)

Virtual reality-based training may improve visual memory and some aspects of sustained attention among healthy older adults – preliminary results of a randomized controlled study

open access: yesBMC Psychiatry
Background/Aims Older age and cognitive inactivity have been associated with cognitive impairment, which in turn is linked to economic and societal burdens due to the high costs of care, especially for care homes and informal care.
Ewa Szczepocka   +10 more
doaj   +1 more source

Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A

open access: yesNeural Plasticity, 2020
Background. Visceral pain is one of the most common types of pain and particularly in the abdomen is associated with gastrointestinal diseases. Bulleyaconitine A (BAA), isolated from Aconitum bulleyanum, is prescribed in China to treat chronic pain.
Sheng-Nan Huang   +5 more
doaj   +1 more source

The difficult task of predicting the costs of community-based mental health care. A comprehensive case register study. [PDF]

open access: yes, 2011
Previous studies have attempted to forecast the costs of mental health care, using clinical and individual variables; the inclusion of ecological measures could improve the knowledge of predictors of psychiatric service utilisation and costs to support ...
Amaddeo, F.   +6 more
core   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Identifying psychosis episodes in psychiatric admission notes via rule-based methods, machine learning, and pre-trained language models

open access: yesTranslational Psychiatry
Early and accurate diagnosis is crucial for effective treatment and improved outcomes, yet identifying psychotic episodes presents significant challenges due to its complex nature and the varied presentation of symptoms among individuals.
Yining Hua   +5 more
doaj   +1 more source

Near-Infrared Stimulation in Psychiatry Disorders: A Systematic Review of Efficacy and Biological Mechanisms

open access: yesNeuroSci
Background: Photobiomodulation (PBM), also referred to as low-level light therapy (LLLT), is an emerging non-pharmacological approach. This treatment is considered low-risk, cost-effective, and non-invasive, utilizing near-infrared light (NIR).
Joanna Woźniak   +3 more
doaj   +1 more source

Aberrant functional connectivity between the amygdala and the temporal pole in drug-free generalized anxiety disorder

open access: yesFrontiers in Human Neuroscience, 2016
The amygdala and the dorsolateral prefrontal cortex (DLPFC) play important roles in emotion dysregulation, which has a profound impact on etiologic research of generalized anxiety disorder (GAD).
Wei Li   +19 more
doaj   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra   +5 more
wiley   +1 more source

Stage-dependent patterns of cognitive network connectivity in early psychosis

open access: yesNature Communications
Cognitive impairments in early psychosis are common, yet prior studies have focused mainly on domain-specific deficits rather than inter-domain relationships.
XiaoChen Tang   +13 more
doaj   +1 more source

Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice

open access: yesMolecular Brain, 2017
Studies have implied that the circadian oscillation of mitogen-activated protein kinase (MAPK) signal pathways is crucial for hippocampus-dependent memory.
Lei Chen   +17 more
doaj   +1 more source

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