Results 11 to 20 of about 113,903 (250)

RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons

Molecular Brain, 2021
Anxiety disorders are the most common psychiatric disorders, and the change in the activity of the prefrontal cortex (PFC) is considered as the underlying pathological mechanism. Parvalbumin-expressing (PV+) inhibition contributes to the overall activity
Ying Sun, Le Ma, Jianhua Chen, Weidi Wang, Shiyu Peng, Ying Cheng, Yu Zhang, Jinghong Chen, Peijun Ju   +8 more
doaj   +1 more source

Living arrangement modifies the associations of loneliness with adverse health outcomes in older adults: evidence from the CLHLS

BMC Geriatrics, 2022
Background Although it has been suggested that loneliness is a risk factor for adverse health outcomes, living arrangement may confound the association.
Kai Wei, Yong Liu, Junjie Yang, Nannan Gu, Xinyi Cao, Xudong Zhao, Lijuan Jiang, Chunbo Li   +7 more
doaj   +1 more source

Psychotic disorders

Abstract There are high rates of psychotic disorders in jails and prisons. Schizophrenia spectrum disorders and substance-induced psychosis are common conditions. Clinical presentations can be complex, and careful assessment and a well-reasoned psychotic disorder diagnosis is the foundation of a sound treatment approach.
Todd Tomita, Rakesh Lamba
  +9 more sources

Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept

International Journal of Bipolar Disorders, 2022
Objective To compare characteristics of bipolar disorder patients diagnosed as DSM-5 types I (BD-1) vs. II (BD-2). Methods We compared descriptive, psychopathological, and treatment characteristics in a sample of 1377 consenting, closely and repeatedly ...
Leonardo Tondo, Alessandro Miola, Marco Pinna, Martina Contu, Ross J. Baldessarini   +4 more
doaj   +1 more source

Comprehensive review of multidimensional biomarkers in the ShangHai At Risk for Psychosis (SHARP) program for early psychosis identification

PCN Reports, 2023
Psychosis is recognized as one of the largest contributors to nonfatal health loss, and early identification can largely improve routine clinical activity by predicting the psychotic course and guiding treatment.
TianHong Zhang, LiHua Xu, XiaoChen Tang, YanYan Wei, YeGang Hu, HuiRu Cui, YingYing Tang, ChunBo Li, JiJun Wang   +8 more
doaj   +1 more source

Elevated pulse pressure and its associations with demographic and clinical parameters in a clinically representative sample of outpatients with psychotic disorders

BJPsych Open, 2022
Elevated pulse pressure is associated with metabolic and neurocognitive diseases. Preliminary small-scale studies among patients with psychotic disorders have indicated that these patients had an increased pulse pressure compared with controls.
Christopher Holmberg, Jarl Torgerson, Andreas Gremyr   +2 more
doaj   +1 more source

Evaluation of the relationship between vitamin D concentration and cognitive performance in community dwelling elderly people

Psychiatria i Psychologia Kliniczna, 2019
Introduction: People over the age of 65 are at a significant risk of vitamin D deficiency. This a result of many factors. Based on the studies conducted so far, it can be concluded that there is a relationship between vitamin D deficiency and the elderly
Katarzyna Antczak-Domagała, Joanna Magierska, Anna Łucka, Jaśmina Arabska, Iwona Kłoszewska, Tomasz Sobów, Radosław Magierski   +6 more
doaj   +1 more source

Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study)

Pharmaceuticals, 2023
Sarcosine (N-methylglycine), a glutamatergic modulator, reduces the primary negative symptoms of schizophrenia. These beneficial changes might be mediated by trophic factors such as epidermal growth factor (EGF).
Agnieszka Pawlak, Bartosz Kaczmarek, Adam Wysokiński, Dominik Strzelecki   +3 more
doaj   +1 more source

20 years of daily hospital for non-psychotic disorders, organisational structure and treatment modalities

European Psychiatry, 2022
Introduction Anxiety and depressive disorders are among the most prevalent psychiatric disorders, yet there aren’t many studies adressing treatment modalities in daily hospitals.
S. Caratan, S. Kocijan Lovko, A. Ivrlač, L. Goršić, T. Matoš   +4 more
doaj   +1 more source

Perceived mental illness stigma and self stigma among persons treated for psychotic disorders

European Psychiatry
Introduction Stigma related to mental health has serious impact on persons suffering from psychiatric disorders and on their families. Self-stigma occurs when people with mental health problems internalize public attitudes, negative beliefs and ...
A. Jambrosic Sakoman, T. Jendričko, D. Bošnjak Kuharić, A. Tomić   +3 more
doaj   +1 more source