Results 41 to 50 of about 1,473,533 (284)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Probiotics as a Treatment for “Metabolic Depression”? A Rationale for Future Studies

Pharmaceuticals, 2021
Depression and metabolic diseases often coexist, having several features in common, e.g., chronic low-grade inflammation and intestinal dysbiosis. Different microbiota interventions have been proposed to be used as a treatment for these disorders. In the
Oliwia Gawlik-Kotelnicka, Dominik Strzelecki   +1 more
doaj   +1 more source

Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu, Sophia F. Damman, Samhitha M. Rai, Hesham Abboud   +3 more
wiley   +1 more source

Relationship Between Cognitive and Clinical Insight at Different Durations of Untreated Attenuated Psychotic Symptoms in High-Risk Individuals

Frontiers in Psychiatry, 2021
Background: This study examines whether cognitive insight is impaired in high-risk individuals with attenuated psychotic symptoms (APS) and explores the relationship between cognitive and clinical insight at different durations of untreated attenuated ...
LiHua Xu, Mei Zhang, ShuQin Wang, YanYan Wei, HuiRu Cui, ZhenYing Qian, YingChan Wang, XiaoChen Tang, YeGang Hu, YingYing Tang, TianHong Zhang, JiJun Wang, JiJun Wang, JiJun Wang   +13 more
doaj   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats

BMC Medical Informatics and Decision Making, 2019
Background Nucleus Accumbens (NAc) is a vital brain region for the process of reward and stress, whereas microRNA plays a crucial role in depression pathology.
Weichen Song, Yifeng Shen, Yanhua Zhang, Sufang Peng, Ran Zhang, Ailing Ning, Huafang Li, Xia Li, Guan Ning Lin, Shunying Yu   +9 more
doaj   +1 more source

Color painting predicts clinical symptoms in chronic schizophrenia patients via deep learning

BMC Psychiatry, 2021
Background Individuals with psychiatric disorders perceive the world differently. Previous studies indicated impaired color vision and weakened color discrimination ability in psychotic patients.
Hui Shen, Shui-Hua Wang, Yi Zhang, Haixia Wang, Feng Li, Molly V. Lucas, Yu-Dong Zhang, Yan Liu, Ti-Fei Yuan   +8 more
doaj   +1 more source

Antioxidant capacity as a novel biomarker of delirium after cardiac surgery

European Psychiatry, 2021
Introduction Coronary-artery bypass graft (CABG) surgery is known to improve cardiac function and decrease mortality, albeit, this method of treatment is associated with a high risk of postoperative delirium.
J. Kaźmierski, A. Pawlak, P. Miler, H. Jerczyńska, J. Woźniak, E. Frankowska, K. Woźniak, A. Brzezińska, M. Wilczyński   +8 more
doaj   +1 more source

Treatment of cannabis use among people with psychotic disorders : critical review of randomised controlled trials

, 2012
There is growing and converging evidence that cannabis may be a major risk factor in people with psychotic disorders and prodromal psychotic symptoms.
Baker, Amanda, Dunlop, Adrian, Thornton, Louise, Hides, Leanne   +3 more
core   +1 more source

Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study [PDF]

, 2022
Background: Psychotic disorders differ in their impact on psychosocial functioning. However, few studies have directly compared psychosocial functioning and its determinants between schizophrenia, schizoaffective disorder (SAD), bipolar disorder (BD ...
Suvisaari, Jaana, Kampman, Olli,, Hakkinen, Katja, Holm, Minna, Wegelius, Asko, Kieseppä, Tuula, Suokas, Kimmo, Lähteenvuo, Markku, Suokas, Kimmo,, Tuulio-Henriksson, Annamari, Ahti, Johan, Holm, Minna,, Kampman, Olli, Isometsä, Erkki,, Tuulio-Henriksson, Annamari,, Isometsä, Erkki, Wegelius, Asko,, Ahti, Johan,, Tiihonen, Jari,, Paunio, Tiina,, Paunio, Tiina, Kieseppä, Tuula,, Suvisaari, Jaana,, Ahola-Olli, Ari, Tiihonen, Jari, Lähteenvuo, Markku,, Häkkinen, Katja,, Ahola-Olli, Ari,, SUPER Researchers Listed Acknowle   +28 more
core   +1 more source