Results 51 to 60 of about 114,482 (250)

Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Behavioral impairment is common in amyotrophic lateral sclerosis (ALS) and strongly affects autonomy, caregiver burden, and outcomes, yet predictors of vulnerability remain unclear. We investigated whether premorbid regulatory traits and socio‐educational exposures are associated with behavioral phenotypes in ALS within a behavioral reserve ...
Francesca Palumbo, Barbara Iazzolino, Cristina Moglia, Umberto Manera, Enrico Matteoni, Sara Cabras, Giorgio Pellegrino, Emilio Minerva, Vita Passidomo, Rosario Vasta, Gabriele Mora, Fabrizio D’Ovidio, Antonio Canosa, Andrea Calvo, Adriano Chiò   +14 more
wiley   +1 more source

Hyperostosis frontalis interna: Observed patterns, prevalence, and dementia associations in older adults

The Anatomical Record, EarlyView.
Abstract Hyperostosis frontalis interna (HFI) is a frequently underrecognized condition characterized by overgrowth of the frontal endocranium, most commonly observed in post‐menopausal women. Although its etiology remains unclear, hormonal influences and a possible relationship with neurocognitive changes have been proposed.
Danielle Felsberg, Kira Morgan, Rickey‐Levon Burch, Madelyn Furr, Zachary Tyson, Steven Lesh   +5 more
wiley   +1 more source

Neurocognitive functioning and emotional recognition in first-episode psychosis: protocol for a follow- up study

European Psychiatry
Introduction Although deficits in neurocognitive functioning and emotional recognition impact treatment outcomes in schizophrenia since the development of the first psychotic episode (FEP), there is still a lack of longer follow-up studies showing the ...
D. Bošnjak Kuharić, P. Makaric, K. Brozic, L. Tomasic, A. Savic, D. Ostojic, M. Rojnic Kuzman   +6 more
doaj   +1 more source

The Unique Roles of Executive Function in Co‐Occurring Psychopathologies in Autism

Autism Research, EarlyView.
ABSTRACT Children with autism spectrum disorder (ASD) often experience co‐occurring psychiatric conditions, such as anxiety and attention‐deficit/hyperactivity disorder (ADHD), which significantly impair daily functioning. However, the underlying mechanisms linking these conditions to core ASD features remain poorly understood.
Shing‐Him Ng, Jet Leung, Keith Chun Lok Lee, Angela Man Wai Lam, Isaac Ho Wai Wong, Sze‐Mai Ng, Maciej Gabrysiak, Petrina Yau Pok Lau, Sandra Sau Man Chan, Tyler M. Moore, Kosha Ruparel, Raquel E. Gur, Ruben C. Gur, Oscar Wing Ho Wong   +13 more
wiley   +1 more source

Virtual reality-based training may improve visual memory and some aspects of sustained attention among healthy older adults – preliminary results of a randomized controlled study

BMC Psychiatry
Background/Aims Older age and cognitive inactivity have been associated with cognitive impairment, which in turn is linked to economic and societal burdens due to the high costs of care, especially for care homes and informal care.
Ewa Szczepocka, Łukasz Mokros, Jakub Kaźmierski, Karina Nowakowska, Anna Łucka, Anna Antoszczyk, Javier Oltra-Cucarella, Walter Werzowa, Martin Hellevik, Stavros Skouras, Karsten Bagger   +10 more
doaj   +1 more source

Bulleyaconitine A Exerts Antianxiety and Antivisceral Hypersensitivity Effects

Frontiers in Pharmacology, 2020
Visceral pain is one of the leading causes for abdominal pain in gastroenterological diseases and is still hard to treat effectively. Bulleyaconitine A (BAA) is an aconitine analog and has been used for the treatment of pain.
Sheng-Nan Huang, Sheng-Nan Huang, BeiBei Yang, Le Ma, Le Ma, Lan-Ting Huang, Pei-Jun Ju, Jinbao Wei, Jinbao Wei, Usman Ali, Usman Ali, Yong-Xiang Wang, Jinghong Chen   +12 more
doaj   +1 more source

Identifying Unique Subgroups of Emotional and Behavioral Presentations in a Large Inpatient and Community Sample of Autistic Youth

Autism Research, EarlyView.
ABSTRACT Autistic youth exhibit wide variability in emotional and behavioral challenges, yet few studies have identified meaningful subgroups based on these profiles. This study applied a random forests ensemble clustering algorithm to item‐level parent‐report data from the Emotion Dysregulation Inventory (EDI) and the Child Behavior Checklist (CBCL ...
Safaa Eldeeb, Jessie Northrup, Caitlin Conner, Shalini Sivathasan, Ligia Antezana, Matthew Siegel, Carla Mazefsky   +6 more
wiley   +1 more source

Identifying psychosis episodes in psychiatric admission notes via rule-based methods, machine learning, and pre-trained language models

Translational Psychiatry
Early and accurate diagnosis is crucial for effective treatment and improved outcomes, yet identifying psychotic episodes presents significant challenges due to its complex nature and the varied presentation of symptoms among individuals.
Yining Hua, Suzanne V. Blackley, Ann K. Shinn, Joseph P. Skinner, Lauren V. Moran, Li Zhou   +5 more
doaj   +1 more source

Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A

Neural Plasticity, 2020
Background. Visceral pain is one of the most common types of pain and particularly in the abdomen is associated with gastrointestinal diseases. Bulleyaconitine A (BAA), isolated from Aconitum bulleyanum, is prescribed in China to treat chronic pain.
Sheng-Nan Huang, Jinbao Wei, Lan-Ting Huang, Pei-Jun Ju, Jinghong Chen, Yong-Xiang Wang   +5 more
doaj   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source